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Title: Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
Author: Dell'Osso, Bernardo
Benatti, Beatrice
Arici, Chiara
Palazzo, Carlotta
Altamura, A. Carlo
Hollander, Eric, 1957-
Fineberg, Naomi
Stein, Dan J., 1962-
Nicolini, Humberto
Lanzagorta, Nuria
Marazziti, Donatella
Pallanti, Stefano
van Ameringen, Michael
Lochner, Christine
Karamustafalioglu, Oguz
Hranov, Luchezar
Figee, Martin
Drummond, Lynne
Rodriguez, Carolyn
Grant, John
Denys, Damiaan
Menchón Magriñá, José Manuel
Zohar, Joseph
Keywords: Neurosi obsessiva
Factors de risc en les malalties
Obsessive-compulsive disorder
Risk factors in diseases
Issue Date: Feb-2018
Publisher: Cambridge University Press
Abstract: OBJECTIVE: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. METHODS: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson's chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. RESULTS: 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. CONCLUSIONS: Our international study found a history of SA prevalence of ~15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.
Note: Versió postprint del document publicat a:
It is part of: Cns Spectrums, 2018, vol. 23, num. 1, p. 59-66
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ISSN: 1092-8529
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)

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