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Title: Measuring cortical thickness with MRI in a transgenic animal model of AD
Author: Pérez Millán, Agnès
Director/Tutor: Tudela Fernández, Raúl
Sala Llonch, Roser
Keywords: Malaltia d'Alzheimer
Escorça cerebral
Ressonància magnètica
Treballs de fi de grau
Alzheimer's disease
Cerebral cortex
Magnetic resonance
Bachelor's thesis
Issue Date: Jan-2019
Abstract: Alzheimer's Disease (AD) is a progressive age-related neurodegenerative disorder, which can be studied through the use of transgenic animal models. AD is characterized by a loss of brain gray matter, resulting in changes in the cortical thickness that can be measured from Magnetic Resonance Imaging (MRI). The present work aimed to measure the cortical thickness from rat brain MRI by creating an automated tailored program implemented in Python and using available algorithms and in-house designed functions. The program was further used to analyse the temporal evolution of the cortical thickness in a transgenic AD model compared to control wild-type rats
Note: Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2019, Tutors: Raúl Tudela, Roser Sala Llonch
Appears in Collections:Treballs Finals de Grau (TFG) - Física

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