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Title: Iron oxide nanoparticles - in vivo/in vitro biomedical applications and in silico studies
Author: Nedyalkova, Miroslava
Donkova, Borjana
Romanova, Julia
Tzvetkov, George
Madurga Díez, Sergio
Simeonov, Vasil
Keywords: Òxid de ferro
Mètode de Montecarlo
Teoria del funcional de densitat
Ferric oxide
Monte Carlo method
Density functionals
Issue Date: 3-May-2017
Publisher: Elsevier
Abstract: The review presents a broad overview of the biomedical applications of surface functionalized iron oxide nanoparticles (IONPs) as magnetic resonance imaging (MRI) agents for sensitive and precise diagnosis tool and synergistic combination with other imaging modalities. Then, the recent progress in therapeutic applications, such as hyperthermia is discussed and the available toxicity data of magnetic nanoparticles concerning in vitro and in vivo biomedical applications are addressed. This review also presents the available computer models using molecular dynamics (MD), Monte Carlo (MC) and density functional theory (DFT), as a basis for a complete understanding of the behaviour and morphology of functionalized IONPs, for improving NPs surface design and expanding the potential applications in nanomedicine.
Note: Versió postprint del document publicat a:
It is part of: Advances in Colloid and Interface Science, 2017, vol. 249, p. 192-212
Related resource:
ISSN: 0001-8686
Appears in Collections:Articles publicats en revistes (Ciència dels Materials i Química Física)

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