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http://hdl.handle.net/2445/147235
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DC Field | Value | Language |
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dc.contributor.author | Cabré, Gisela | - |
dc.contributor.author | Garrido Charles, Aida | - |
dc.contributor.author | González Lafont, Àngels | - |
dc.contributor.author | Moormann, Widukind | - |
dc.contributor.author | Langbehn, Daniel | - |
dc.contributor.author | Egea, David | - |
dc.contributor.author | Lluch, José M. | - |
dc.contributor.author | Herges, Rainer | - |
dc.contributor.author | Alibés, Ramon | - |
dc.contributor.author | Busqué, Félix | - |
dc.contributor.author | Gorostiza Langa, Pablo Ignacio | - |
dc.contributor.author | Hernando, Jordi | - |
dc.date.accessioned | 2020-01-08T15:34:40Z | - |
dc.date.available | 2020-05-09T05:10:18Z | - |
dc.date.issued | 2019-05-09 | - |
dc.identifier.uri | http://hdl.handle.net/2445/147235 | - |
dc.description.abstract | Photoswitchable neurotransmitters of ionotropic kainate receptors were synthesized by tethering a glutamate moiety to disubstituted C2-bridged azobenzenes, which were prepared through a novel methodology that allows access to diazocines with higher yields and versatility. Because of the singular properties of these photochromes, photoisomerizable compounds were obtained with larger thermal stability for their inert cis isomer than for their biologically activity trans state. This enabled selective neuronal firing upon irradiation without background activity in the dark. | ca |
dc.format.extent | 5 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | ca |
dc.publisher | American Chemical Society | ca |
dc.relation.isformatof | Versió postprint document publicat a: https://doi.org/10.1021/acs.orglett.9b01222 | - |
dc.relation.ispartof | Organic Letters, 2019, vol. 21, num. 10, p. 3780-3784 | - |
dc.relation.uri | https://doi.org/10.1021/acs.orglett.9b01222 | - |
dc.rights | (c) American Chemical Society, 2019 | - |
dc.source | Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) | - |
dc.subject.classification | Pèptids | - |
dc.subject.classification | Proteïnes | - |
dc.subject.classification | Monòmers | - |
dc.subject.other | Peptides | - |
dc.subject.other | Proteins | - |
dc.subject.other | Monomers | - |
dc.title | Synthetic Photoswitchable Neurotransmitters Based on Bridged Azobenzenes | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/785907/EU//HBP_SGA2 | ca |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 31070376 | - |
Appears in Collections: | Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) Publicacions de projectes de recerca finançats per la UE |
Files in This Item:
File | Description | Size | Format | |
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L01_2019_Organic Letters_21_3780_OA.pdf | 609.65 kB | Adobe PDF | View/Open |
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