Please use this identifier to cite or link to this item:
Title: Lithium and bipolar depression
Author: Manchia, Mirko
Rybakowski, Janusz K.
Sani, Gabriele
Kessing, Lars V.
Murru, Andrea
Alda, Martin
Tondo, Leonardo
Keywords: Trastorn bipolar
Manic-depressive illness
Issue Date: 26-Apr-2019
Publisher: John Wiley & Sons
Abstract: Kelly1 has recently disputed the recommendations of several international guidelines on the use of lithium in bipolar depression. In his scrutiny, the author points to three main errors that seem to have affected systematically ten international guidelines, namely the Woozle effect (evidence by citation), reference inflation (inappropriate citation of pivotal, generally old, studies) and belief perseverance (inability to modify evidence‐based recommendations despite the presence of contrary data). We concur with the author that the evidence supporting the effectiveness of lithium in acute bipolar depression, and to a lesser degree also in major depressive episodes, remains inadequate.2, 3 A different matter is, in our opinion, to label guidelines recommendations as inaccurate or biased, even if, as the author stated, no deceptive intentions were present.
Note: Versió postprint del document publicat a:
It is part of: Bipolar Disorders, 2019, vol. 21, num. 5, p. 458-459
Related resource:
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Files in This Item:
File Description SizeFormat 
12474_4944228_manchia_et_al_2019_bipol_disord_li_and_bdepression.pdf212.92 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.