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http://hdl.handle.net/2445/149469
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DC Field | Value | Language |
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dc.contributor.author | Sullivan, Ann K. | - |
dc.contributor.author | Raben, Dorthe | - |
dc.contributor.author | Reekie, Joanne | - |
dc.contributor.author | Rayment, Michael | - |
dc.contributor.author | Mocroft, Amanda | - |
dc.contributor.author | Esser, Stefan | - |
dc.contributor.author | León García, Agathe | - |
dc.contributor.author | Begovac, Josip | - |
dc.contributor.author | Brinkman, Kees | - |
dc.contributor.author | Zangerle, Robert | - |
dc.contributor.author | Grzeszczuk, Anna | - |
dc.contributor.author | Vassilenko, Anna | - |
dc.contributor.author | Hadziosmanovic, Vesna | - |
dc.contributor.author | Krasnov, Maksym | - |
dc.contributor.author | Sönnerborg, Anders | - |
dc.contributor.author | Clumeck, Nathan | - |
dc.contributor.author | Gatell, José M. | - |
dc.contributor.author | Gazzard, Brian | - |
dc.contributor.author | Arminio Monforte, Antonella d' | - |
dc.contributor.author | Rockstroh, Jürgen Kurt | - |
dc.contributor.author | Lundgren, Jens D. | - |
dc.date.accessioned | 2020-02-05T15:19:34Z | - |
dc.date.available | 2020-02-05T15:19:34Z | - |
dc.date.issued | 2013-01-15 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://hdl.handle.net/2445/149469 | - |
dc.description.abstract | Improved methods for targeting HIV testing among patients most likely to be infected are required; HIDES I aimed to define the methodology of a European wide study of HIV prevalence in individuals presenting with one of eight indicator conditions/diseases (ID); sexually transmitted infection, lymphoma, cervical or anal cancer/dysplasia, herpes zoster, hepatitis B/C, mononucleosis-like illness, unexplained leukocytopenia/thrombocytopenia and seborrheic dermatitis/exanthema, and to identify those with an HIV prevalence of >0.1%, a level determined to be cost effective. A staff questionnaire was performed. From October 2009- February 2011, individuals, not known to be HIV positive, presenting with one of the ID were offered an HIV test; additional information was collected on previous HIV testing behaviour and recent medical history. A total of 3588 individuals from 16 centres were included. Sixty-six tested positive for HIV, giving an HIV prevalence of 1.8% [95% CI: 1.42-2.34]; all eight ID exceeded 0.1% prevalence. Of those testing HIV positive, 83% were male, 58% identified as MSM and 9% were injecting drug users. Twenty percent reported previously having potentially HIV-related symptoms and 52% had previously tested HIV negative (median time since last test: 1.58 years); which together with the median CD4 count at diagnosis (400 cell/uL) adds weight to this strategy being effective in diagnosing HIV at an earlier stage. A positive test was more likely for non-white individuals, MSM, injecting drug users and those testing in non-Northern regions. HIDES I describes an effective strategy to detect undiagnosed HIV infection. All eight ID fulfilled the >0.1% criterion for cost effectiveness. All individuals presenting to any health care setting with one of these ID should be strongly recommended an HIV test. A strategy is being developed in collaboration with ECDC and WHO Europe to guide the implementation of this novel public health initiative across Europe. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0052845 | - |
dc.relation.ispartof | PLoS One, 2013, vol. 8, num. 1 | - |
dc.relation.uri | https://doi.org/10.1371/journal.pone.0052845 | - |
dc.rights | cc-by (c) Sullivan, Ann K. et al., 2013 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | VIH (Virus) | - |
dc.subject.classification | Infeccions per VIH | - |
dc.subject.other | HIV (Viruses) | - |
dc.subject.other | HIV infections | - |
dc.title | Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study) | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 635575 | - |
dc.date.updated | 2020-02-05T15:19:34Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 23341910 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) |
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635575.pdf | 208.42 kB | Adobe PDF | View/Open |
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