Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió acceptadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/151388
A critical retrospective and prospective review of designs and materials in in-line solid-phase extraction capillary electrophoresis
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Resum
Several strategies have been developed to decrease the concentration limits of detection (LODs) in capillary electrophoresis (CE). Nowadays, chromatographic-based preconcentration using a microcartridge integrated in the separation capillary for in-line solid-phase extraction capillary electrophoresis (SPE-CE) is one of the best alternatives for high throughput and reproducible sample clean-up and analyte preconcentration. This review covers different designs (geometrical configurations, with frits or fritless, capillary types, compatibility with commercial instrumentation, etc.) and materials (sorbents, supports, affinity ligands, etc.) applied for almost 30 years to prepare in-line SPE-CE microcartridges (i.e. analyte concentrators), with emphasis on the conventional unidirectional configuration in capillary format. Advantages, disadvantages and future perspectives are analyzed in detail to provide the reader a wide overview about the great potential of this technique to enhance sensitivity and address trace analysis.
Descripció
Matèries (anglès)
Citació
Citació
PONT VILLANUEVA, Laura, PERÓ GASCÓN, Roger, GIMÉNEZ LÓPEZ, Estela, SANZ NEBOT, María victoria, BENAVENTE MORENO, Fernando j. (julián). A critical retrospective and prospective review of designs and materials in in-line solid-phase extraction capillary electrophoresis. _Analytica Chimica Acta_. 2019. Vol. 1079, núm. 1-19. [consulta: 5 de desembre de 2025]. ISSN: 0003-2670. [Disponible a: https://hdl.handle.net/2445/151388]