Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/152523
Title: | 'Head-to-side-chain' cyclodepsipeptides of marine origin |
Author: | Pelay Gimeno, Marta Tulla-Puche, Judit Albericio Palomera, Fernando |
Keywords: | Productes naturals Medicaments peptídics Poliquets Natural products Peptide drugs Polychaeta |
Issue Date: | 21-May-2013 |
Publisher: | MDPI |
Abstract: | Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as "head-to-side-chain" cyclodepsipeptides, have been isolated and characterized. These peptides present a unique structural arrangement that comprises a macrocyclic region closed through an ester bond between the C-terminus and a β-hydroxyl group, and terminated with a polyketide moiety or a more simple branched aliphatic acid. This structural pattern, the presence of unique and complex residues, and relevant bioactivity are the main features shared by all the members of this new class of depsipeptides, which are reviewed herein. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/md11051693 |
It is part of: | Marine Drugs, 2013, vol. 11, num. 5, p. 1693-1717 |
URI: | http://hdl.handle.net/2445/152523 |
Related resource: | https://doi.org/10.3390/md11051693 |
ISSN: | 1660-3397 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
658236.pdf | 1.51 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License