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http://hdl.handle.net/2445/152583
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DC Field | Value | Language |
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dc.contributor.author | Osorio Durango, Edison Javier | - |
dc.contributor.author | Londoño, Julián | - |
dc.contributor.author | Bastida Armengol, Jaume | - |
dc.date.accessioned | 2020-03-11T16:11:47Z | - |
dc.date.available | 2020-03-11T16:11:47Z | - |
dc.date.issued | 2013-05-22 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | http://hdl.handle.net/2445/152583 | - |
dc.description.abstract | Six biflavonoids were isolated from G. madruno, one of which, 7''-O-(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu2+, was studied by means of a TBARS assay. The antioxidant potential of a biflavonoid fraction (BF) was also evaluated and correlated with its biflavonoid content. The flavanone-(3→8'')-flavone biflavonoids displayed antioxidant activity, particularly morelloflavone, which was significantly more potent than quercetin, with a CE50 of 12.36 μg/mL. Lipid peroxidation, was also significantly reduced in the presence of the BF (EC50 = 11.85 μg/mL). These results suggest that the BF is an excellent antioxidant. | - |
dc.format.extent | 9 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/molecules18056092 | - |
dc.relation.ispartof | Molecules, 2013, vol. 18, num. 5, p. 6092-6100 | - |
dc.relation.uri | https://doi.org/10.3390/molecules18056092 | - |
dc.rights | cc-by (c) Osorio, Edison et al., 2013 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) | - |
dc.subject.classification | Gutíferes | - |
dc.subject.classification | Antioxidants | - |
dc.subject.classification | Flavonoides | - |
dc.subject.classification | Glucòsids | - |
dc.subject.other | Guttiferae | - |
dc.subject.other | Antioxidants | - |
dc.subject.other | Flavonoids | - |
dc.subject.other | Glucosides | - |
dc.title | Low-density lipoprotein (LDL)-antioxidant biflavonoids from Garcinia madruno | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 636822 | - |
dc.date.updated | 2020-03-11T16:11:47Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 23698056 | - |
Appears in Collections: | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) |
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636822.pdf | 258.7 kB | Adobe PDF | View/Open |
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