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Title: Low-cost impedance measurements for lab-on-a-chip architectures: Towards potentiostat miniaturization
Author: Pruna Morales, Raquel
Palacio Bonet, Francisco
Baraket, Abdoullatif
Bausells, Joan
Errachid, Abdelhamid
López de Miguel, Manuel
Keywords: Espectroscòpia d'impedància
Insuficiència cardíaca
Amplificadors (Electrònica)
Impedance spectroscopy
Heart failure
Amplifiers (Electronics)
Issue Date: 28-Aug-2017
Publisher: MDPI
Abstract: The development of miniaturized potentiostats capable of measuring in a wide range of conditions and with full characteristics (e.g., wide bandwidth and capacitive/inductive contribution to sensor's impedance) is still an unresolved challenge in bioelectronics. We present a simple analogue design coupled to a digital filter based on a lock-in amplifier as an alternative to complex architectures reported hitherto. A low-cost, miniaturized and fully integrated acquisition electronic system was developed, tested for a fully integrated three-lead electrochemical biosensor and benchmarked against a commercial potentiostat. The portable potentiostat was coupled to an array of miniaturized gold working electrodes to perform complex impedance analyses for tumor necrosis factor α (TNF-α) cytokine detection. This wearable potentiostat is very promising for the development of low-cost point-of-care (POC) with low power consumption.
Note: Reproducció del document publicat a:
It is part of: MDPI Proceedings, 2017, vol. 1, num. 4, p. 604
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ISSN: 2504-3900
Appears in Collections:Articles publicats en revistes (Enginyeria Electrònica i Biomèdica)

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