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Title: The role of platelet-activating factor antagonists in the prohylasis of postransplant acute tubular necrosis
Author: Grinyó Boira, Josep M.
Torras Ambròs, Joan
Valles, Joaquim
Keywords: Trasplantament renal
Agregació plaquetària
Kidney transplantation
Blood platelet aggregation
Issue Date: 1-May-1996
Publisher: Marcel Dekker
Abstract: Renal reperfusion injury can be defined as the renal damage suffered by a kidney because of reestablishment of blood flow prolonged ischemia. Increased permeability for calcium ions, subsequent activation of endogenous phospholipases, and damage mediated by oxygen free radicals are involved in this reperfusion injury. Inhibition of inflammatory mediators of endothelial origin, such as superoxide radicals and platelet-activating factor (PAF), is a possible way of protecting the injured endothelium following blood reperfusion.
Note: Reproducció del document publicat a:
It is part of: Renal Failure, 1996, vol. 18, num. 3, p. 445-451
Related resource:
ISSN: 0886-022X
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)

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