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http://hdl.handle.net/2445/157647| Title: | Phakillestatins: an underwater unsolved puzzle |
| Author: | Meli, Alessandra Tedesco, Consiglia Della Sala, Giorgio Schettini, Rosaria Albericio Palomera, Fernando de Riccardis, Francesco Izzo, Irene |
| Keywords: | Aminoàcids Síntesi de pèptids Farmacologia Amino acids Peptide synthesis Pharmacology |
| Issue Date: | 18-Mar-2017 |
| Publisher: | MDPI |
| Abstract: | A critical summary on the discovery of the nineteen members of the phakellistatin family (phakellistatin 1-19), cytotoxic proline‐rich cyclopeptides of marine origin, is reported. Isolation, structural elucidation, and biological properties of the various‐sized natural macrocycles are described, along with the total syntheses and the enigmatic issues of the cytotoxic activity reproducibility. |
| Note: | Reproducció del document publicat a: https://doi.org/10.3390/md15030078 |
| It is part of: | Marine Drugs, 2017, vol. 15, num. 3, p. 78 |
| URI: | http://hdl.handle.net/2445/157647 |
| Related resource: | https://doi.org/10.3390/md15030078 |
| ISSN: | 1660-3397 |
| Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) Publicacions de projectes de recerca finançats per la UE |
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| 681090.pdf | 584.62 kB | Adobe PDF | View/Open |
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