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Title: Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies
Author: Ulaszewska, Marynka M.
Weinert, Christoph H.
Trimigno, Alessia
Portmann, Reto
Andrés Lacueva, Ma. Cristina
Badertscher, René
Brennan, Lorraine
Brunius, Carl
Bub, Achim
Capozzi, Francesco
Cialiè Rosso, Marta
Cordero, Chiara E.
Daniel, Hannelore
Durand, Stephanie
Egert, Bjoern
Ferrario, Paola G.
Feskens, Edith J. M.
Franceschi, Pietro
Garcia Aloy, Mar
Giacomoni, Franck
Giesbertz, Pieter
González Domínguez, Raúl
Hanhineva, Kati
Hemeryck, Lieselot Y.
Kopka, Joachim
Kulling, Sabine
Llorach, Rafael
Manach, Claudine
Mattivi, Fulvio
Migné, Carole
Münger, Linda H.
Ott, Beate
Picone, Gianfranco
Pimentel, Grégory
Pujos Guillot, Estelle
Riccadonna, Samantha
Rist, Manuela
Rombout, Caroline
Rubert, Josep
Skurk, Thomas
Sri Harsha, Pedapati S. C.
Van Meulebroek, Lieven
Vanhaecke, Lynn
Vázquez Fresno, Rosa
Wishard, David
Vergères, Guy
Keywords: Ciències de la vida
Life sciences
Issue Date: 2019
Publisher: Wiley-VCH
Abstract: The life sciences are currently being transformed by an unprecedented wave of developments in molecular analysis, which include important advances in instrumental analysis as well as biocomputing. In light of the central role played by metabolism in nutrition, metabolomics is rapidly being established as a key analytical tool in human nutritional studies. Consequently, an increasing number of nutritionists integrate metabolomics into their study designs. Within this dynamic landscape, the potential of nutritional metabolomics (nutrimetabolomics) to be translated into a science, which can impact on health policies, still needs to be realized. A key element to reach this goal is the ability of the research community to join, to collectively make the best use of the potential offered by nutritional metabolomics. This article, therefore, provides a methodological description of nutritional metabolomics that reflects on the state‐of‐the‐art techniques used in the laboratories of the Food Biomarker Alliance (funded by the European Joint Programming Initiative "A Healthy Diet for a Healthy Life" (JPI HDHL)) as well as points of reflections to harmonize this field. It is not intended to be exhaustive but rather to present a pragmatic guidance on metabolomic methodologies, providing readers with useful "tips and tricks" along the analytical workflow.
Note: Versió postprint del document publicat a:
It is part of: Molecular Nutrition & Food Research, 2019, vol. 63, num. 1, p. 1800384
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ISSN: 1613-4125
Appears in Collections:Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Institut de Recerca en Nutrició i Seguretat Alimentària (INSA·UB))

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