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http://hdl.handle.net/2445/160840
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DC Field | Value | Language |
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dc.contributor.author | Agramunt, Jordi | - |
dc.contributor.author | Ginesi, Rebecca | - |
dc.contributor.author | Pedroso Muller, Enrique | - |
dc.contributor.author | Grandas Sagarra, Anna | - |
dc.date.accessioned | 2020-05-18T08:04:31Z | - |
dc.date.available | 2021-04-22T05:10:20Z | - |
dc.date.issued | 2020-04-22 | - |
dc.identifier.issn | 0022-3263 | - |
dc.identifier.uri | http://hdl.handle.net/2445/160840 | - |
dc.description.abstract | Oligonucleotides, peptides, and peptide nucleic acids incorporating 7-oxanorbornene as a dienophile were reacted with tetrazines linked to either a peptide, d-biotin, BODIPY, or N-acetyl-d-galactosamine. The inverse electron-demand Diels-Alder (IEDDA) cycloaddition, which was performed overnight at 37 °C, in all cases furnished the target conjugate in good yields. IEDDA reactions with 7-oxanorbornenes produce a lower number of stereoisomers than that of IEDDA cycloadditions with other dienophiles. | - |
dc.format.extent | 12 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | American Chemical Society | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1021/acs.joc.0c00583 | - |
dc.relation.ispartof | Journal of Organic Chemistry, 2020, vol. 85, num. 10, p. 6593-6604 | - |
dc.relation.uri | https://doi.org/10.1021/acs.joc.0c00583 | - |
dc.rights | (c) American Chemical Society , 2020 | - |
dc.source | Articles publicats en revistes (Química Inorgànica i Orgànica) | - |
dc.subject.classification | Solucions (Química) | - |
dc.subject.classification | Pèptids | - |
dc.subject.classification | Proteïnes | - |
dc.subject.classification | Biopolímers | - |
dc.subject.classification | Dissolvents | - |
dc.subject.other | Solution (Chemistry) | - |
dc.subject.other | Peptides | - |
dc.subject.other | Proteins | - |
dc.subject.other | Biopolymers | - |
dc.subject.other | Solvents | - |
dc.title | Inverse electron-demand Diels-Alder bioconjugation using 7-oxanorbornenes as dienophiles | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 700346 | - |
dc.date.updated | 2020-05-18T08:04:31Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
Files in This Item:
File | Description | Size | Format | |
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700346.pdf | 1.05 MB | Adobe PDF | View/Open |
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