Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/160887
Title: Derisking Development by a Cocrystallization Screen of a Novel Selective Inhaled JAK-STAT inhibitor
Author: Llinàs, Antonio
Barbas Cañero, Rafael
Font Bardia, Ma. Mercedes
Smailagic, A.
Prohens López, Rafael
Keywords: Cristal·lografia
Sals
Crystallography
Salts
Issue Date: Oct-2019
Publisher: American Chemical Society
Abstract: The discovery and detailed characterization of several new solid forms of a novel selective inhaled JAK-STAT inhibitor are described. Using a holistic cocrystallization screen approach to explore its formulation landscape, we decrease the risk of future potential development failures due to a nonoptimal pharmacokinetic lung profile or undesired lung effects in humans.
Note: Versió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.8b01492
It is part of: Crystal Growth & Design, 2019, vol. 19, num. 1, p. 403-414
URI: http://hdl.handle.net/2445/160887
Related resource: https://doi.org/10.1021/acs.cgd.8b01492
ISSN: 1528-7483
Appears in Collections:Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)

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