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Title: Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
Author: Tsang, John S.
Dobaño, Carlota, 1969-
VanDamme, Pierre
Moncunill, Gemma
Marchant, Arnaud
Othman, Rym Ben
Sadarangani, Manish
Koff, Wayne C.
Kollmann, Tobias R.
Keywords: Vacunació
Issue Date: 8-Apr-2020
Publisher: Elsevier B.V.
Abstract: Immune signatures measured at baseline and immediately prior to vaccination may predict the immune response to vaccination. Such pre-vaccine assessment might allow not only population-based, but also more personalized vaccination strategies ('precision vaccination'). If baseline immune signatures are predictive, the underlying mechanism they reflect may also determine vaccination outcome. Thus, baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses. This concept has the potential to transform vaccination strategies and usher in a new approach to improve global health.
Note: Reproducció del document publicat a:
It is part of: Trends In Immunology , 2020 , Online ahead of print
Related resource: 10.1016/
ISSN: 1471-4906
Appears in Collections:Articles publicats en revistes (ISGlobal)

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