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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/163721
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dc.contributor.authorPaulo de Andrade, Jean-
dc.contributor.authorGiordani, R. B.-
dc.contributor.authorTorras Claveria, Laura-
dc.contributor.authorPigni, Natalia Belén-
dc.contributor.authorBerkov, Strahil-
dc.contributor.authorFont Bardia, Ma. Mercedes-
dc.contributor.authorCalvet Pallàs, Maria Teresa-
dc.contributor.authorKonrath, E.-
dc.contributor.authorBueno, K.-
dc.contributor.authorSachett, L. G.-
dc.contributor.authorDutilh, J. H.-
dc.contributor.authorBorges, W. D.-
dc.contributor.authorViladomat Meya, Francesc-
dc.contributor.authorHenriques, A. T.-
dc.contributor.authorNair, Jerald J.-
dc.contributor.authorZuanazzi, José Ângelo Silveira-
dc.contributor.authorBastida Armengol, Jaume-
dc.date.accessioned2020-06-02T11:13:06Z-
dc.date.available2020-06-02T11:13:06Z-
dc.date.issued2016-02-
dc.identifier.issn1568-7767-
dc.identifier.urihttp://hdl.handle.net/2445/163721-
dc.description.abstractNine Brazilian Amaryllidaceae species were studied for their alkaloid composition and acetylcholinesterase (AChE) inhibitory activity via GC-MS and a modified Ellman assay, respectively. A total of thirty-six alkaloids were identified in these plants, of which Hippeastrum papilio and H. glau-cescens exhibited the highest galanthamine content and the best IC50 values against AChE. Furthermore, Hippeastrum vittatum and Rhodophiala bifida also showed notable AChE inhibitory effects. X-ray crys-tallographic data for four galanthamine-type com-pounds revealed significant differences in the orientation of theN-methyl group, which are shown to be related to AChE inhibition.-
dc.format.extent24 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherSpringer Science + Business Media-
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1007/s11101-015-9411-7-
dc.relation.ispartofPhytochemistry Reviews, 2016, vol. 15, num. 1, p. 147-160-
dc.relation.urihttps://doi.org/10.1007/s11101-015-9411-7-
dc.rights(c) Springer Science + Business Media, 2016-
dc.sourceArticles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)-
dc.subject.classificationAlcaloides-
dc.subject.classificationRadiocristal·lografia-
dc.subject.otherAlkaloids-
dc.subject.otherX-ray crystallography-
dc.titleThe brazilian Amaryllidaceae as a source of acetylcholinesterase inhibitory alkaloids-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.identifier.idgrec656974-
dc.date.updated2020-06-02T11:13:06Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
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