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Title: Synthesis and Antiviral Evaluation of Bisnoradamantane Sulfites and Related Compounds
Author: Valverde Murillo, Elena
Torres Costa, Eva
Guardiola Bagán, Salvadorr
Naesens, Lieve
Vázquez Cruz, Santiago
Keywords: Sulfits
Medicaments antivírics
Síntesi de fàrmacs
Antiviral agents
Drug synthesis
Issue Date: 2-Oct-2011
Publisher: Bentham Science Publishers
Abstract: The reaction of a series of 1,2-diols with thionyl chloride led to bisnoradamantane sulfites in very good yields. The reaction has also been applied to related polycyclic scaffolds. The compounds have been tested for antiviral activity but none of them showed to be active. Several attempts to generate and trap SO from these polycyclic sulfites have been unsuccessful.
Note: Versió postprint del document publicat a:
It is part of: Medicinal Chemistry, 2011, vol. 7, num. 2, p. 135-140
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ISSN: 1573-4064
Appears in Collections:Divulgació i Premsa (Genètica, Microbiologia i Estadística)
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Articles publicats en revistes (Institut de Biomedicina (IBUB))

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