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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/164358
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dc.contributor.authorAmat Tusón, Mercedes-
dc.contributor.authorLlor Brunés, Núria-
dc.contributor.authorCheca Castaño, Begoña-
dc.contributor.authorMolins i Grau, Elies-
dc.contributor.authorBosch Cartes, Joan-
dc.date.accessioned2020-06-04T17:03:03Z-
dc.date.available2020-06-04T17:03:03Z-
dc.date.issued2010-01-01-
dc.identifier.issn0022-3263-
dc.identifier.urihttp://hdl.handle.net/2445/164358-
dc.description.abstractStarting from an appropriate unsaturated phenylglycinol-derived oxazolopiperidone lactam, the synthesis of (-)-16-episilicine is reported, the key steps being a stereoselective conjugate addition, a stereoselective alkylation, and a ring-closing metathesis reaction. This represents the first enantioselective total synthesis of an alkaloid of the silicine group.-
dc.format.extent12 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherAmerican Chemical Society-
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1021/jo902346j-
dc.relation.ispartofJournal of Organic Chemistry, 2010, vol. 75, num. 1, p. 178-189-
dc.relation.urihttps://doi.org/10.1021/jo902346j-
dc.rights(c) American Chemical Society , 2010-
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)-
dc.subject.classificationAlcaloides-
dc.subject.classificationLactames-
dc.subject.classificationSíntesi asimètrica-
dc.subject.otherAlkaloids-
dc.subject.otherLactams-
dc.subject.otherAsymmetric synthesis-
dc.titleA synthetic approach to ervatamine-silicine alkaloids. Enantioselective total synthesis of (-)-episilicine-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.identifier.idgrec579163-
dc.date.updated2020-06-04T17:03:03Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid19968261-
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Articles publicats en revistes (Institut de Biomedicina (IBUB))

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