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http://hdl.handle.net/2445/165290
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DC Field | Value | Language |
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dc.contributor.author | Llinàs, Antonio | - |
dc.contributor.author | Barbas Cañero, Rafael | - |
dc.contributor.author | Font Bardia, Ma. Mercedes | - |
dc.contributor.author | Quayle, M. J. | - |
dc.contributor.author | Velaga, S. | - |
dc.contributor.author | Prohens López, Rafael | - |
dc.date.accessioned | 2020-06-12T07:21:37Z | - |
dc.date.available | 2020-06-12T07:21:37Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1528-7483 | - |
dc.identifier.uri | http://hdl.handle.net/2445/165290 | - |
dc.description.abstract | Two new cocrystals of zafirlukast with piperazine, existing in five different solid forms, have been discovered during a cocrystal screening. The crystal structure of one of these forms has been determined by single crystal X-ray diffraction, and the stability landscape of the crystalline forms of the new cocrystal has been studied. In the present article, we extend the knowledge about the solid state of this important pharmaceutical drug for the treatment of asthma by reporting the crystal structures of two new solvates (acetonitrile and butanol) and the elusive anhydrous Form X, which have been solved by single crystal X-ray diffraction. | - |
dc.format.extent | 34 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | American Chemical Society | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.5b00744 | - |
dc.relation.ispartof | Crystal Growth & Design, 2015, vol. 15, num. 8, p. 4162-4169 | - |
dc.relation.uri | https://doi.org/10.1021/acs.cgd.5b00744 | - |
dc.rights | (c) American Chemical Society , 2015 | - |
dc.source | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) | - |
dc.subject.classification | Estructura cristal·lina (Sòlids) | - |
dc.subject.classification | Química supramolecular | - |
dc.subject.other | Layer structure (Solids) | - |
dc.subject.other | Supramolecular chemistry | - |
dc.title | Two New Polymorphic Cocrystals of Zafirlukast: Preparation, Crystal Structure, and Stability Relations | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 693069 | - |
dc.date.updated | 2020-06-12T07:21:37Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) |
Files in This Item:
File | Description | Size | Format | |
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693069.pdf | 2.09 MB | Adobe PDF | View/Open |
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