Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/165543
Title: | Microwave-Assisted Synthesis of Substituted Pyrrolo[2,3-d]pyrimidines |
Author: | Prieur, Vanessa Rubio Martínez, Jaime Font Bardia, Ma. Mercedes Guillaumet, Gérald Pujol Dilmé, M. Dolors |
Keywords: | Nitrogen Microones Nitrogen Microwaves |
Issue Date: | 2-Feb-2014 |
Publisher: | Wiley-VCH |
Abstract: | A new synthetic routes to the triaryl pyrrolo[2,3-d]pyrimidines from common 4,6-dichloropyrimidine have been developed. The triarylated compounds are synthesized by three cross-coupling reactions using three different catalysts. The introduction of C-6-aryl was allowed in two step process using Sonogashira conditions followed by intramolecular cyclization and the Suzuki-Miyaura conditions led the C-4 and C-5 diarylation. This sequence allows a flexible approach to the highly arylated pyrrolopyrimidines containing different aryl groups |
Note: | Versió postprint del document publicat a: https://doi.org/10.1002/ejoc.201301496 |
It is part of: | European Journal of Organic Chemistry, 2014, vol. 2014, num. 7, p. 1514-1524 |
URI: | http://hdl.handle.net/2445/165543 |
Related resource: | https://doi.org/10.1002/ejoc.201301496 |
ISSN: | 1434-193X |
Appears in Collections: | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) |
Files in This Item:
File | Description | Size | Format | |
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636482.pdf | 1.89 MB | Adobe PDF | View/Open |
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