Please use this identifier to cite or link to this item:
Title: Microwave-Assisted Synthesis of Substituted Pyrrolo[2,3-d]pyrimidines
Author: Prieur, Vanessa
Rubio Martínez, Jaime
Font Bardia, Ma. Mercedes
Guillaumet, Gérald
Pujol Dilmé, M. Dolors
Keywords: Nitrogen
Issue Date: 2-Feb-2014
Publisher: Wiley-VCH
Abstract: A new synthetic routes to the triaryl pyrrolo[2,3-d]pyrimidines from common 4,6-dichloropyrimidine have been developed. The triarylated compounds are synthesized by three cross-coupling reactions using three different catalysts. The introduction of C-6-aryl was allowed in two step process using Sonogashira conditions followed by intramolecular cyclization and the Suzuki-Miyaura conditions led the C-4 and C-5 diarylation. This sequence allows a flexible approach to the highly arylated pyrrolopyrimidines containing different aryl groups
Note: Versió postprint del document publicat a:
It is part of: European Journal of Organic Chemistry, 2014, vol. 2014, num. 7, p. 1514-1524
Related resource:
ISSN: 1434-193X
Appears in Collections:Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)

Files in This Item:
File Description SizeFormat 
636482.pdf1.89 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.