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Title: Combining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance
Author: Brouwer-Brolsma, Elske M.
Brennan, Lorraine
Drevon, Christian A
van Kranen, Henk
Manach, Claudine
Dragsted, Lars O.
Roche, Helen M.
Andrés Lacueva, Ma. Cristina
Bakker, Stephan J. L.
Bouwman, Jildau
Capozzi, Francesco
De Saeger, Sarah
Gundersen, Thomas E.
Kolehmainen, Marjukka
Kulling, Sabine
Landberg, Rikard
Linseisen, Jakob
Mattivi, Fulvio
Mensink, Ronald P.
Scaccini, Cristina
Skurk, Thomas
Tetens, Inge
Vergères, Guy
Wishart, David S.
Scalbert, Augustin
Feskens, Edith J. M.
Keywords: Metabolòmica
Marcadors bioquímics
Biochemical markers
Issue Date: 4-Nov-2017
Publisher: Cambridge University Press
Abstract: FFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health. Keywords: Dietary assessment; Food intake biomarkers; Food metabolome; Metabolomics.
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It is part of: Proceedings of the Nutrition Society, 2017, vol. 76, num. 5, p. 619-627
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ISSN: 0029-6651
Appears in Collections:Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

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