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Title: An overview of nanomedicines for neuron targeting
Author: Garcia-Chica, Jesús
Paraiso, West Kristian D.
Tanabe, Shihori
Serra i Cucurull, Dolors
Herrero Rodríguez, Laura
Casals, Núria
García Gómez, Jordi
Ariza Piquer, Xavier
Quader, Sabina
Rodriguez-Rodriguez, Rosalia
Keywords: Nanopartícules
Malalties cerebrals
Administració de medicaments
Brain diseases
Administration of drugs
Issue Date: 3-Jul-2020
Publisher: Future Medicine
Abstract: Medical treatments of neuron-related disorders are limited due to the difficulty of targeting brain cells. Major drawbacks are the presence of the blood-brain barrier and the lack of specificity of the drugs for the diseased cells. Nanomedicine-based approaches provide promising opportunities for overcoming these limitations. Although many previous reviews are focused on brain targeting with nanomedicines in general, none of those are concerned explicitly on the neurons, while targeting neuronal cells in central nervous diseases is now one of the biggest challenges in nanomedicine and neuroscience. We review the most relevant advances in nanomedicine design and strategies for neuronal drug delivery that might successfully bridge the gap between laboratory and bedside treatment in neurology.
Note: Versió postprint del document publicat a:
It is part of: Nanomedicine, 2020, vol. 15, num. 16, p. 1617-1636
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ISSN: 1743-5889
Appears in Collections:Articles publicats en revistes (Química Inorgànica i Orgànica)

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