Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/169354
Title: Biological properties of extracellular vesicles and their physiological functions
Author: Yáñez-Mó, María
Siljander, Pia R.M.
Andreu, Zoraida
Bedina Zavec, Apolonija
Borràs, Francesc E.
Buzas, Edit I.
Buzas, Krisztina
Casal, Enriqueta
Cappello, Francesco
Carvalho, Joana
Colás, Eva
Cordeiro-da Silva, Anabela
Fais, Stefano
Falcon-Perez, Juan M.
Ghobrial, Irene M.
Giebel, Bernd
Gimona, Mario
Graner, Michael
Gursel, Ihsan
Gursel, Mayda
Heegaard, Niels H. H.
Hendrix, An
Kierulf, Peter
Kokubun, Katsutoshi
Kosanović, Maja M.
Kralj-Iglic, Veronika
Krämer-Albers, Eva-Maria
Laitinen, Saara
Lässer, Cecilia
Lener, Thomas
Ligeti, Erzsébet
Oliveira, Carla
Pállinger, Éva
Lipps, Georg
Llorente, Alicia
Lötvall, Jan
Portillo, Hernando A. del
Rigau, Marina
Olivan Riera, Mireia
Reventós Puigjaner, Jaume
Keywords: Vesícules seminals
Fisiologia
Espai extracel·lular
Seminal vesicles
Physiology
Extracellular space
Issue Date: 14-May-2015
Publisher: Taylor & Francis Group
Abstract: In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influencing various physiological and pathological functions of both recipient and parent cells. While intensive investigation has targeted the role of EVs in different pathological processes, for example, in cancer and autoimmune diseases, the EV-mediated maintenance of homeostasis and the regulation of physiological functions have remained less explored. Here, we provide a comprehensive overview of the current understanding of the physiological roles of EVs, which has been written by crowd-sourcing, drawing on the unique EV expertise of academia-based scientists, clinicians and industry based in 27 European countries, the United States and Australia. This review is intended to be of relevance to both researchers already working on EV biology and to newcomers who will encounter this universal cell biological system. Therefore, here we address the molecular contents and functions of EVs in various tissues and body fluids from cell systems to organs. We also review the physiological mechanisms of EVs in bacteria, lower eukaryotes and plants to highlight the functional uniformity of this emerging communication system.
Note: Reproducció del document publicat a: https://doi.org/10.3402/jev.v4.27066
It is part of: Journal Of Extracellular Vesicles, 2015, vol. 4, p. 27066
URI: http://hdl.handle.net/2445/169354
Related resource: https://doi.org/10.3402/jev.v4.27066
ISSN: 2001-3078
Appears in Collections:Articles publicats en revistes (Patologia i Terapèutica Experimental)

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