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Title: Computational analysis of signal dynamics induced by ligands
Author: Mut Sbert, Macià
Director/Tutor: Ibañes Miguez, Marta
Keywords: Lligands (Bioquímica)
Formació de patrons (Física)
Treballs de fi de grau
Ligands (Biochemistry)
Pattern formation (Physical sciences
Bachelor's thesis
Issue Date: Jun-2020
Abstract: During tissue development, cells differentiate creating a cellular pattern thanks to communication frameworks like the one studied, the Notch signalling pathway. In such mechanisms a cell interacts with the surrounding cells through proteins called ligands. With a numerical simulation program we manage to confirm the formation of cell patterns and doing a lineal stability analysis we find under which conditions the pattern can arise for a sustained signal activation. Furthermore, when implementing a transitory pulsating signal dynamics we find that a minimum interaction time is required if the cells are to differentiate
Note: Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2020, Tutora: Marta Ibañes Miguez
Appears in Collections:Treballs Finals de Grau (TFG) - Física

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