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http://hdl.handle.net/2445/171392
Title: | Computational analysis of signal dynamics induced by ligands |
Author: | Mut Sbert, Macià |
Director/Tutor: | Ibañes Miguez, Marta |
Keywords: | Lligands (Bioquímica) Formació de patrons (Física) Treballs de fi de grau Ligands (Biochemistry) Pattern formation (Physical sciences Bachelor's theses |
Issue Date: | Jun-2020 |
Abstract: | During tissue development, cells differentiate creating a cellular pattern thanks to communication frameworks like the one studied, the Notch signalling pathway. In such mechanisms a cell interacts with the surrounding cells through proteins called ligands. With a numerical simulation program we manage to confirm the formation of cell patterns and doing a lineal stability analysis we find under which conditions the pattern can arise for a sustained signal activation. Furthermore, when implementing a transitory pulsating signal dynamics we find that a minimum interaction time is required if the cells are to differentiate |
Note: | Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2020, Tutora: Marta Ibañes Miguez |
URI: | http://hdl.handle.net/2445/171392 |
Appears in Collections: | Treballs Finals de Grau (TFG) - Física |
Files in This Item:
File | Description | Size | Format | |
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MUT SBERT MACIÀ_1338784_assignsubmission_file_TFG_Mut_Sbert_Macia.pdf | 798.44 kB | Adobe PDF | View/Open |
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