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Title: | Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication |
Author: | Bellet, Meritxell Ahmad, Faten Villanueva, Rafael Valdivia, Carolina Palomino Doza, Julián Ruiz, Ada Gonzalez-Farre, Xavier Adrover, Encarna Azaro, Analía Valls Margarit, Maria Parra, Josep Lluís Aguilar Company, Juan Vidal Losada, Maria Jesús Martin, Anastasi Gavilá, Joaquín Escrivá de Romaní, Santiago Perelló, Antonia Hernando, Cristina Lahuerta, Ainhara Zamora, Pilar Reyes, Victoria Alcalde, María Masanas, Helena Celiz, Pamela Ruiz, Isabel Gil Gil, Miguel Seguí, Miguel Àngel Peña, Lorena de la |
Keywords: | Càncer de mama Oncologia Breast cancer Oncology |
Issue Date: | 1-May-2019 |
Publisher: | Sage Publications Ltd. |
Abstract: | Drug-drug interactions are of significant concern in clinical practice in oncology, particularly in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically exposed to long-term regimens. This article presents the highlights from the 'First Workshop on Pharmacology and Management of CDK4/6 Inhibitors: Consensus about Concomitant Medications'. The article is structured into two modules. The educational module includes background information regarding drug metabolism, corrected QT (QTc) interval abnormalities, management of psychotropic drugs and a comprehensive review of selected adverse effects of palbociclib and ribociclib. The collaborative module presents the conclusions of the five working groups, each of which comprised five experts from different fields. From these conclusions positive lists of drugs for treating common comorbid conditions that can be safely administered concomitantly with palbociclib and/or ribociclib were developed. |
Note: | Reproducció del document publicat a: https://doi.org/10.1177/1758835919833867 |
It is part of: | Therapeutic Advances in Medical Oncology, 2019, vol. 11 |
URI: | http://hdl.handle.net/2445/171556 |
Related resource: | https://doi.org/10.1177/1758835919833867 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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