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Title: Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
Author: Cassol Spanemberg, Juliana
Blanco Carrión, Andrés
Rodríguez de Rivera Campillo, Ma Eugenia
Estrugo Devesa, Albert
Jané Salas, Enric
López López, José, 1958-
Keywords: Liquen pla
Manifestacions orals de les malalties
Aparell genital
Lichen planus
Oral manifestations of general diseases
Generative organs
Issue Date: 1-Jan-2019
Publisher: Medicina Oral SL
Abstract: Background: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptive study reviewed 274 clinical histories of patients, who all presented histological confirmation of lichen planus verified by a pathologist, attending research centers in Barcelona. Results: A total of 40 LP patients (14.59%) presented genital lesions. Of 131 patients with cutaneous LP (47.8%), the most commonly affected zones were the body's flexor surfaces, representing 60.1% of cases. 24% of patients (n=55) related the start of the lesions with previous stress events. Of the 131 subjects with cutaneous lesions, 19% (n=25) also presented oral lichen planus (OLP). Of the total sample, 53.6% (n=147) of patients presented oral lesions. The systemic diseases most commonly associated with this patient sample were psychological problems such as stress, anxiety and depression (48%), hypertension (27%), gastric problems (12%), and diabetes (9.7%). A family history of lichen planus was found in only 2 cases (0,72%) out of the total of 274. Conclusions: Any patient with OLP should undergo a thorough history and examination to investigate potential extraoral manifestations. The fact that 37 patients with OLP in this patient series were identified with simultaneous involvement at more than one site highlights the need for thorough evaluation and multidisciplinary approaches to this disease.
Note: Reproducció del document publicat a:
It is part of: Medicina Oral, Patología Oral y Cirugía Bucal, 2019, vol. 24, num. 1, p. 1-7
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ISSN: 1698-4447
Appears in Collections:Articles publicats en revistes (Odontoestomatologia)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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