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Title: SIRT2 in age-related neurodegenerative disorders
Author: Fourcade, Stéphane
Outeiro, Tiago F.
Pujol Onofre, Aurora
Keywords: Malalties neurodegeneratives
Neurodegenerative diseases
Issue Date: 1-Mar-2018
Publisher: Impact Journals Llc.
Abstract: Sirtuin 2 (SIRT2) is one of seven members of the NAD+-dependent histone deacetylases (HDAC) family of proteins. Sirtuins play diverse roles in cellular metabolism and the aging process. SIRT2 is located in the nucleus, cytoplasm, and mitochondria, is highly expressed in the central nervous system (CNS), and has been reported to regulate a variety of processes including oxidative stress, genome integrity, and myelination [1].
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It is part of: Aging-us, 2018, vol. 10, num. 3, p. 295-296
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Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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