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http://hdl.handle.net/2445/172734| Title: | Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas |
| Author: | Gallardo, Fernando Esteller, Manel Pujol, Ramon M. Costa, Carlota Estrach Panella, Ma. Teresa (María Teresa) Servitje Bedate, Octavio |
| Keywords: | Genètica Limfomes Cèl·lules T Genetics Lymphomas T cells |
| Issue Date: | 1-Nov-2004 |
| Publisher: | Ferrata Storti Foundation |
| Abstract: | p15(INK4b), p16(INK4a) and O(6)-methylguanine DNA methyltransferase (MGMT) gene hypermethylation was studied in 22 patients with primary cutaneous T-cell lymphomas (CTCL). p15(INK4b) and p16(INK4a) inactivation is present in early and advanced disease and seems to be independent of disease stage. MGMT inactivation may play a pathogenetic role in a subset of CTCL. |
| Note: | Reproducció del document publicat a: https://haematologica.org/issue/view/124 |
| It is part of: | Haematologica, 2004, vol. 89, num. 11, p. 1401-1403 |
| URI: | http://hdl.handle.net/2445/172734 |
| ISSN: | 0390-6078 |
| Appears in Collections: | Articles publicats en revistes (Ciències Fisiològiques) Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Medicina) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 521069.pdf | 135.89 kB | Adobe PDF | View/Open |
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