Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/172734
Title: | Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas |
Author: | Gallardo, F. (Fernando) Esteller, Manel Pujol, Ramon M. Costa, Carlota Estrach Panella, Ma. Teresa (María Teresa) Servitje Bedate, Octavio |
Keywords: | Genètica Limfomes Cèl·lules T Genetics Lymphomas T cells |
Issue Date: | 1-Nov-2004 |
Publisher: | Ferrata Storti Foundation |
Abstract: | p15(INK4b), p16(INK4a) and O(6)-methylguanine DNA methyltransferase (MGMT) gene hypermethylation was studied in 22 patients with primary cutaneous T-cell lymphomas (CTCL). p15(INK4b) and p16(INK4a) inactivation is present in early and advanced disease and seems to be independent of disease stage. MGMT inactivation may play a pathogenetic role in a subset of CTCL. |
Note: | Reproducció del document publicat a: https://haematologica.org/issue/view/124 |
It is part of: | Haematologica, 2004, vol. 89, num. 11, p. 1401-1403 |
URI: | http://hdl.handle.net/2445/172734 |
ISSN: | 0390-6078 |
Appears in Collections: | Articles publicats en revistes (Ciències Fisiològiques) Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Medicina) |
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