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dc.contributor.authorGiménez, Sandra-
dc.contributor.authorVidela, Laura-
dc.contributor.authorRomero, Sergio-
dc.contributor.authorBenejam, Bessy-
dc.contributor.authorClos, Susana-
dc.contributor.authorFernández, Susana-
dc.contributor.authorMartínez, Maribel-
dc.contributor.authorCarmona-Iragui, Maria-
dc.contributor.authorAntonijoan Arbós, Rosa Ma. (Rosa María)-
dc.contributor.authorMayos, Mercedes-
dc.contributor.authorFortuna, Ana-
dc.contributor.authorPeñacoba, Patricia-
dc.contributor.authorPlaza, Vicente-
dc.contributor.authorOsorio, Ricardo S.-
dc.contributor.authorSharma, Ram A.-
dc.contributor.authorBardés, Ignasi-
dc.contributor.authorRebillat, Anne Sophie-
dc.contributor.authorLleó Bisa, Alberto-
dc.contributor.authorBlesa González, Rafael-
dc.contributor.authorVidela, Sebas-
dc.contributor.authorFortea Ormaechea, Juan-
dc.description.abstractSTUDY OBJECTIVES:Sleep problems are often undetected in adults with Down syndrome (DS). Our objective was to determine the prevalence of sleep disorders in adults with DS through self-reported and objective sleep measures. METHODS:We performed a community-based cross-sectional study of 54 adults with DS not referred for sleep disorders. Two polysomnography (PSG) sleep studies were performed. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI); daytime sleepiness was evaluated using the Epworth Sleepiness Scale (ESS) and the risk for the sleep apnea syndrome (OSA) was identified using the Berlin Questionnaire (BQ). Participants' sleep/wake pattern was assessed from sleep diaries and by wrist actigraphy. PSQI, ESS, and PSG measures were compared with 35 sex-, age-, and body mass index-matched patients in the control groups. RESULTS:In PSG measures, adults with DS showed lower sleep efficiency (69 ± 17.7 versus 81.6 ± 11; P < .001), less rapid eye movement sleep (9.4 ± 5.8 versus 19.4 ± 5.1; P < .001), a higher prevalence of OSA (78% versus 14%; P < .001), and a higher apnea-hypopnea index (23.5 ± 24.5 versus 3.8 ± 10.5; P < .001) than patients in the control group. In the DS group, the questionnaires (mean PSQI 3.7 ± 2.9; mean ESS 6.3 ± 4.5 and mean BQ 1 ± 0) did not reflect the sleep disturbances detected on the PSG. Actigraphy data recorded daytime sleep that was not self-reported (118.2 ± 104.2 minutes). CONCLUSIONS:Adults with DS show severe sleep disruption and a high prevalence of OSA, undetected by self-reported sleep measures. Actigraphy, PSG, and validated simplified devices for screening OSA should be routinely recommended for this population because treatment of sleep disorders can contribute to healthy aging.-
dc.format.extent9 p.-
dc.publisherAmerican Academy of Sleep Medicine-
dc.relation.isformatofVersió postprint del document publicat a:
dc.relation.ispartofJournal of Clinical Sleep Medicine, 2018, vol. 14, num. 10, p. 1725-1733-
dc.rights(c) American Academy of Sleep Medicine, 2018-
dc.subject.classificationSíndrome de Down-
dc.subject.classificationTrastorns del son-
dc.subject.otherDown syndrome-
dc.subject.otherSleep disorders-
dc.titlePrevalence of sleep disorders in adults with down syndrome: a comparative study of subjective, actigraphic and polygraphic findings-
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Patologia i Terapèutica Experimental)

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