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http://hdl.handle.net/2445/173321
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DC Field | Value | Language |
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dc.contributor.author | Moreno Llorente, Pablo | - |
dc.contributor.author | Quintana Basarrate, Aitor de la | - |
dc.contributor.author | Musholt, Thomas J. | - |
dc.contributor.author | Paunovic, Ivan | - |
dc.contributor.author | Puccini, Marco | - |
dc.contributor.author | Vidal Pérez, Oscar | - |
dc.contributor.author | Ortega, Joaquín | - |
dc.contributor.author | Kraimps, Jean-Louis | - |
dc.contributor.author | European Study Group for Metastatic Adrenalectomy | - |
dc.date.accessioned | 2021-01-21T13:39:26Z | - |
dc.date.available | 2021-01-21T13:39:26Z | - |
dc.date.issued | 2020-09-01 | - |
dc.identifier.issn | 2227-684X | - |
dc.identifier.uri | http://hdl.handle.net/2445/173321 | - |
dc.description.abstract | Background: The outcome of adrenalectomy carried out by laparoscopy or open surgery for solid tumor metastases was assessed. Methods: A total of 317 patients with histologically confirmed adrenal metastatic disease collected from 30 centres in Europe underwent adrenalectomy by laparoscopy (n=146) or open laparotomy (n=171). Differences between laparoscopic and open adrenalectomy were assessed by a single Cox analysis for both procedures. Results: The median overall survival was 24.0 [95% confidence interval (CI): 21.4-26.6] months for open adrenalectomy and 45.0 (95% CI: 22.6-67.4) for laparoscopic adrenalectomy (P=0.008). Survival rates were 68%, 49%, 35% and 29% at 1, 2, 3 and 5 years for open surgery vs. 88%, 62%, 52% and 46% for laparoscopy, respectively. In the subgroup of R0 resections, the difference in survival in favor of laparoscopy (median 46 vs. 27 months) was marginally significant (P=0.073). Renal cancer [hazard ratio (HR) 0.42; 95% CI: 0.23-0.76, P=0.005], surgery of the primary tumor (HR 0.33; 95% CI: 0.19-0.54), and use of chemotherapy (HR 0.62; 95% CI: 0.43-0.88) were associated with a better survival, whereas type of resection (R1/R2 vs. R0) was associated with a worse prognosis (HR 2.29; 95% CI: 1.52-3.44, P<0.001). Conclusions: Laparoscopic adrenalectomy patients showed a longer survival than open adrenalectomy individuals, as minimally invasive approach was attempted more common in less advanced disease which led to higher number of R0 resections. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | AME Publishing Company | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.21037/gs.2019.10.15 | - |
dc.relation.ispartof | Gland Surgery, 2020, vol. 9, num. 2, p. 159-165 | - |
dc.relation.uri | https://doi.org/10.21037/gs.2019.10.15 | - |
dc.rights | cc-by-nc-nd (c) AME Publishing Company, 2020 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Laparoscòpia | - |
dc.subject.classification | Metàstasi | - |
dc.subject.classification | Tumors | - |
dc.subject.other | Laparoscopy | - |
dc.subject.other | Metastasis | - |
dc.subject.other | Tumors | - |
dc.title | Laparoscopy versus open adrenalectomy in patients with solid tumor metastases: results of a multicenter European study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 699602 | - |
dc.date.updated | 2021-01-21T13:39:26Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 32175257 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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