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http://hdl.handle.net/2445/173759
Title: | Real-life effect of a microcrystalline tyrosine adjuvanted mite immunotherapy in patients with allergic rhinitis |
Author: | Roger, Albert Malet, Alfons Moreno, Victoria Parra, Antonio Gutierrez, Diego Lleonart Bellfill, Ramón Moreno, Francisco Valero, Antonio Navarro, Begoña Hinojosa, Belén Justicia, José L. |
Keywords: | Àcars Rinitis Mites Rhinitis |
Issue Date: | 1-Jan-2020 |
Publisher: | Future Medicine Ltd. |
Abstract: | Aim: Evaluate the effectiveness and safety of immunotherapy with Acarovac Plus((R)) in a 1-year prospective multicentered real-life study. Methods: A total of 118 adults with allergic rhinitis sensitized to Dermatophagoides received subcutaneous immunotherapy with Acarovac Plus. Treatment outcomes were evaluated at baseline, 6 months and 1 year after treatment initiation. Primary end point was the evolution of the combined symptom and medication score. Secondary end points included other effectiveness outcomes and measurement of product tolerability. Results: Acarovac Plus induced significant improvements in primary and secondary end points after 6 months compared with baseline. These differences persisted after 1 year of treatment (p < 0.001; baseline vs 1 year): combined symptom and medication score (1.60 vs 0.79). No serious adverse events were recorded. Conclusion: Acarovac Plus for 1 year was effective and well tolerated in a real-life setting. |
Note: | Reproducció del document publicat a: https://doi.org/10.2217/imt-2019-0205 |
It is part of: | Immunotherapy, 2020, vol. 12, num. 1, p. 53-62 |
URI: | http://hdl.handle.net/2445/173759 |
Related resource: | https://doi.org/10.2217/imt-2019-0205 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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