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http://hdl.handle.net/2445/174124
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DC Field | Value | Language |
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dc.contributor.author | Wikman Jorgensen, Philip Erick | - |
dc.contributor.author | Llenas García, Jara | - |
dc.contributor.author | Shedrawy, Jad | - |
dc.contributor.author | Gascón i Brustenga, Joaquim | - |
dc.contributor.author | Muñoz Gutiérrez, José | - |
dc.contributor.author | Bisoffi, Zeno | - |
dc.contributor.author | Requena-Méndez, Ana | - |
dc.date.accessioned | 2021-02-22T11:36:12Z | - |
dc.date.available | 2021-02-22T11:36:12Z | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 2059-7908 | - |
dc.identifier.uri | http://hdl.handle.net/2445/174124 | - |
dc.description.abstract | Background: The best strategy for controlling morbidity due to imported strongyloidiasis in migrants is unclear. We evaluate the cost-effectiveness of six possible interventions. Methods: We developed a stochastic Markov chain model. The target population was adult migrants from endemic countries to the European Union; the time horizon, a lifetime and the perspective, that of the health system. Average and incremental cost-effectiveness ratios (ACER and ICER) were calculated as 2016 EUR/life-year gained (LYG). Health interventions compared were: base case (no programme), primary care-based presumptive treatment (PCPresTr), primary care-based serological screening and treatment (PCSerTr), hospital-based presumptive treatment (HospPresTr), hospital-based serological screening and treatment (HospSerTr), hospital-based presumptive treatment of immunosuppressed (HospPresTrim) and hospital-based serological screening and treatment of the immunosuppressed (HospSerTrim). The willingness to pay threshold (WTP) was ¿32 126.95/LYG. Results: The base case model yielded a loss of 2 486 708.24 life-years and cost EUR 3 238 393. Other interventions showed the following: PCPresTr: 2 488 095.47 life-years (Δ1 387.23LYG), cost: EUR 8 194 563; ACER: EUR 3573/LYG; PCSerTr: 2 488 085.8 life-years (Δ1377.57LYG), cost: EUR 207 679 077, ACER: EUR 148 407/LYG; HospPresTr: 2 488 046.17 life-years (Δ1337.92LYG), cost: EUR 14 559 575; ACER: EUR 8462/LYG; HospSerTr: 2 488 024.33 life-years (Δ1316.08LYG); cost: EUR 207 734 073; ACER: EUR 155 382/LYG; HospPresTrim: 2 488 093.93 life-years, cost: EUR 1 105 483; ACER: EUR -1539/LYG (cost savings); HospSerTrim: 2 488 073.8 life-years (Δ1365.55LYG), cost: EUR 4 274 239; ACER: EUR 759/LYG. One-way and probabilistic sensitivity analyses were undertaken; HospPresTrim remained below WTP for all parameters' ranges and iterations. Conclusion: Presumptively treating all immunosuppressed migrants from areas with endemic Strongyloides would generate cost savings to the health system. | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | BMJ Publishing Group | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1136/bmjgh-2020-002321 | - |
dc.relation.ispartof | BMJ Global Health, 2020, vol. 5(5), num. e002321 | - |
dc.relation.uri | https://doi.org/10.1136/bmjgh-2020-002321 | - |
dc.rights | cc-by-nc (c) Wikman Jorgensen, Philip Erick et al., 2020 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/3.0/es | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Infeccions | - |
dc.subject.classification | Migrants | - |
dc.subject.classification | Cost de l'assistència sanitària | - |
dc.subject.other | Infections | - |
dc.subject.other | Migrants | - |
dc.subject.other | Cost of medical care | - |
dc.title | Cost-effectiveness of Different Strategies for Screening and Treatment of Strongyloides stercoralis in Migrants From Endemic Countries to the European Union | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 701485 | - |
dc.date.updated | 2021-02-22T11:36:12Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 32461226 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (ISGlobal) |
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File | Description | Size | Format | |
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701485.pdf | 1.61 MB | Adobe PDF | View/Open |
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