Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/174218
Title: Characterization of Mucosal Lesions in Crohn's Disease Scored With Capsule Endoscopy: A Systematic Review
Author: Marquès Camí, Miquel
Serracarbasa, Alba
D'Haens, Geert
Löwenberg, Mark
Keywords: Malaltia de Crohn
Malalties inflamatòries intestinals
Crohn's disease
Inflammatory bowel diseases
Issue Date: 14-Jan-2021
Publisher: Frontiers Media
Abstract: Background and Aims: There is little agreement on the nomenclature and description of Crohn’s disease (CD) lesions that can be found in the small and large bowel using capsule endoscopy (CE). We performed a systematic review to identify mucosal lesions that have been described using CE in CD, in both the small bowel and colon, with the aim to make propositions to homogenize such descriptions. Methods: A systematic literature search was conducted using Embase, Medline (OvidSP), and Cochrane Central on August 6, 2019. Clinical studies providing nomenclature and descriptions for small bowel and colonic inflammatory lesions using CE in CD were selected for data collection. Results: In total, 851 articles were included for abstract screening out of which 219 were analyzed for full-text review. Twenty-two articles were selected for data extraction. Seven items, accompanied by clear descriptions, were found for the small bowel: i.e., ulcer, erosion, aphthoid lesion, edema, fissure, cobblestone appearance, and villous atrophy. No studies were found describing inflammatory items using CE in colonic CD. Conclusions: The most frequently described CD lesions using CE were ulcers and erosions. Subjective interpretation of CE inflammatory findings plays an important role. Based on our findings, a range of suggestions regarding items and descriptions is made that might form the basis of a pan-enteric CE activity index.
Note: Reproducció del document publicat a: https://doi.org/10.3389/fmed.2020.600095
It is part of: Frontiers in Medicine, 2021, vol. 7
URI: http://hdl.handle.net/2445/174218
Related resource: https://doi.org/10.3389/fmed.2020.600095
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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