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DC Field | Value | Language |
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dc.contributor.author | Hernández Rojas, Zojaina | - |
dc.contributor.author | Dalmau Llorca, Maria Rosa | - |
dc.contributor.author | Aguilar Martín, Carina | - |
dc.contributor.author | Gonçalves, Alessandra Queiroga | - |
dc.contributor.author | Casajuana, Marc | - |
dc.contributor.author | Fernández Sáez, José | - |
dc.contributor.author | Rodríguez Cumplido, Dolores | - |
dc.contributor.author | Forcadell Drago, Emma | - |
dc.contributor.author | Carrasco Querol, Noèlia | - |
dc.contributor.author | Pepió i Vilaubí, Josep M. | - |
dc.contributor.author | Alegret, Josep M. | - |
dc.date.accessioned | 2021-03-03T11:42:28Z | - |
dc.date.available | 2021-03-03T11:42:28Z | - |
dc.date.issued | 2020-09-04 | - |
dc.identifier.uri | http://hdl.handle.net/2445/174574 | - |
dc.description.abstract | Background: Anticoagulant therapy is used for stroke prevention and proved to be effective and safe in the long term. The study aims to analyse the cost-effectiveness relationship of using of direct-acting oral anticoagulants vs vitamin K antagonists to prevent ischaemic stroke in patients with nonvalvular atrial fibrillation, including all the active ingredients marketed in Spain, prescribed for 2 years in the Primary Care service of the Institut Català de la Salut. Methods: Population-based cohort study, in which the cost of the 2 treatment groups will be evaluated. Direct costs (pharmacy, primary care, emergency and hospitalization) and indirect costs (lost productivity) will be included from a social perspective. Effectiveness (assessed as the occurrence of a health event, the 1 of primary interest being stroke) will be determined, with a 2-year time horizon and a 3% discount rate. The average cost of the 2 groups of drugs will be compared using a regression model to determine the factors with the greatest influence on determining costs. We will carry out a univariate ('one-way') deterministic sensitivity analysis. Discussion: We hope to provide relevant information about direct and indirect costs of oral anticoagulants, which, together with aspects of effectiveness and safety, could help shape the consensual decision-making of evaluating bodies. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Ovid Technologies (Wolters Kluwer Health) | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1097/MD.0000000000022054 | - |
dc.relation.ispartof | Medicine, 2020, vol. 99 (36), num. e22054 | - |
dc.relation.uri | https://doi.org/10.1097/MD.0000000000022054 | - |
dc.rights | cc by (c) Hernández Rojas, Zojaina et al., 2020 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Cost de l'assistència sanitària | - |
dc.subject.classification | Catalunya | - |
dc.subject.classification | Assaigs clínics | - |
dc.subject.classification | Anticoagulants (Medicina) | - |
dc.subject.classification | Vitamines K | - |
dc.subject.other | Cost of medical care | - |
dc.subject.other | Catalonia | - |
dc.subject.other | Clinical trials | - |
dc.subject.other | Anticoagulants (Medicine) | - |
dc.subject.other | Vitamin K | - |
dc.title | Cost-effectiveness of direct oral anticoagulants versus vitamin K antagonist in atrial fibrillation: A study protocol using Real-World Data from Catalonia (FantasTIC Study) | - |
dc.type | info:eu-repo/semantics/article | - |
dc.date.updated | 2021-03-02T10:44:45Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 32899067 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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Cost_effectiveness_of_direct_oral_anticoagulants.79.pdf | 281.63 kB | Adobe PDF | View/Open |
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