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Title: Incidence and regression of metabolic syndrome in a representative sample of the Spanish population: results of the cohort study
Author: Cuesta, Martín
Fuentes, Manuel
Rubio, Miguel
Bordiú, Elena
Barabash, Ana
García de la Torre, Nuria
Rojo Martínez, Gemma
Valdes, Sergio
Soriguer, Federico
Vendrell, Joan Josep
Urrutia, Ines Maria
Ortega, Emilio
Montanya Mias, Eduard
Menendez, Eldelmiro
Lago Sampedro, Ana
Gomis, Ramon, 1946-
Goday Arnó, Albert
Castell, Conxa
Badia Guillén, Rocío
Girbés, Juan
Gaztambide, Sonia
Franch Nadal, Josep
Delgado Álvarez, Elías
Chaves, Felipe Javier
Castano, Luis
Calle Pascual, Alfonso L.
Keywords: Estils de vida
Síndrome metabòlica
Metabolic syndrome
Issue Date: 2020
Publisher: BMJ Publishing Group Ltd.
Abstract: Introduction: Metabolic syndrome (MetS) is an important predictor of cardiovascular mortality. Identification of occurrence and regression trends of MetS could permit elaboration of preventive strategies with new targets. The objective of this study was to analyze the occurrence and regression rates of MetS and its associated factors in the representative cohort of Spain of the study. Research design and methods: The study is a prospective cohort where 5072 people representative of the Spanish population over 18 years of age were randomly selected between 2009 and 2010. Follow-up was a median of 7.5 (IQR 7.2-7.9) years, with 2408 (47%) participating subjects. A total of 1881 (78%) subjects had all the pertinent data available and were included in this study. Results: Of the 1146 subjects without baseline criteria for MetS, 294 (25.7%) developed MetS during follow-up, while of the 735 patients with prior MetS, 148 (20.1%) presented regression. Adjusted MetS incidence per 1000 person-years was 38 (95% CI 32 to 44), while regression incidence was 36 (95% CI 31 to 41). Regression rate was independently higher than incidence rate in the following: women, subjects aged 18-45, university-degree holders, patients without central obesity, without hypertension, as well as those with body mass index of <25 kg/m(2). Lower progression and higher regression rates were observed with an adapted 14-point Mediterranean Diet adherence screener questionnaire score of >11 in both groups and with >500 and >2000 MET-min/week of physical activity, respectively. Conclusions: This study provides MetS incidence and regression rates, and identifies the target population for intervention strategies in Spain and possibly in other countries.
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It is part of: BMJ Open Diabetes Research and Care, 2020, vol. 8, num. 1
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Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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