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http://hdl.handle.net/2445/175110
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DC Field | Value | Language |
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dc.contributor.author | Corral, Javier | - |
dc.contributor.author | Parés, David | - |
dc.contributor.author | García Cuyás, Francesc | - |
dc.contributor.author | Revollo, Boris | - |
dc.contributor.author | Chamorro, Ana | - |
dc.contributor.author | Lecumberri, Carla | - |
dc.contributor.author | Tarrats, Antoni | - |
dc.contributor.author | Castella, Eva | - |
dc.contributor.author | Piñol, Marta | - |
dc.contributor.author | Clotet, Bonaventura, 1953- | - |
dc.contributor.author | Videla, Sebas | - |
dc.contributor.author | Sirera, Guillem | - |
dc.date.accessioned | 2021-03-15T12:27:32Z | - |
dc.date.available | 2021-03-15T12:27:32Z | - |
dc.date.issued | 2021-02-14 | - |
dc.identifier.uri | http://hdl.handle.net/2445/175110 | - |
dc.description.abstract | This single-center, retrospective cohort study sought to estimate the cumulative incidence in HIV-1-infected patients of biopsy-proven high-grade anal intraepithelial neoplasia (HGAIN) recurrence after infrared coagulation (IRC) treatment. The study was based on data from a prospectively compiled database of 665 HIV-1-infected outpatients who attended a hospital Clinical Proctology/HIV Unit between January 2012 and December 2015. Patient records were checked to see which ones had received IRC treatment but later experienced a recurrence of HGAIN. Cytology samples were also checked for the presence of human papilloma virus (HPV). A total of 81 of the 665 patients (12%, 95%CI: 10-15%), of whom 65 were men and 16 women, were diagnosed with HGAIN and again treated with IRC. Of these 81, 20 (25%) experienced recurrent HGAIN, this incidence being true of both men (16/65, 95%CI: 19-57%) and women (4/16, 95%CI: 10-50%). The median time to recurrence was 6 (2-19) months overall, 6 (2-19) months in men, and 4 (2-6) months in women. HPV infection was detected in all patients except two, with HPV-16 being the most common genotype. This rate of incidence of recurrent HGAIN following IRC treatment is consistent with other reports and highlights the importance of continued post-treatment surveillance, particularly in the first year. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI AG | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/pathogens10020208 | - |
dc.relation.ispartof | Pathogens, 2021, vol. 10, num. 208 | - |
dc.relation.uri | https://doi.org/10.3390/pathogens10020208 | - |
dc.rights | cc by (c) Corral, Javier et al., 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Patologia i Terapèutica Experimental) | - |
dc.subject.classification | Infeccions per VIH | - |
dc.subject.classification | Malalties de l'anus | - |
dc.subject.other | HIV infections | - |
dc.subject.other | Diseases of the anus | - |
dc.title | Incidence of Recurrent High-Grade Anal Dysplasia in HIV-1-Infected Men and Women Following Infrared Coagulation Ablation: A Retrospective Cohort Study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.identifier.idgrec | 710619 | - |
dc.date.updated | 2021-03-11T11:16:01Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 33672969 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) Articles publicats en revistes (Patologia i Terapèutica Experimental) |
Files in This Item:
File | Description | Size | Format | |
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pathogens-10-00208-v2.pdf | 229.28 kB | Adobe PDF | View/Open |
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