Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/175175
Title: Spleen rupture in a case of untreated Plasmodium vivax infection
Author: Machado Siqueira, André
Lopes Magalhães, Belisa Maria
Cardoso Melo, Gisely
Ferrer, Mireia
Castillo, Paola
Martín Jaular, Lorena
Fernández Becerra, Carmen
Ordi i Majà, Jaume
Martínez, Antonio
Guimarães Lacerda, Marcus Vinícius
Portillo Obando, Hernando A. del
Keywords: Plasmodium vivax
Malalties parasitàries
Malària
Plasmodium vivax
Parasitic diseases
Malaria
Issue Date: 13-Dec-2012
Publisher: Public Library of Science (PLoS)
Abstract: We report the unique case of a 19-yearold nonimmune patient with Plasmodium vivax monoinfection, confirmed by PCR in the peripheral blood and in the spleen section, who was splenectomized due to spleen rupture two days prior to the diagnosis and treatment of the malarial infection. Microscopic analyses evidenced white pulp expansion and a diffuse hypercellularity in the splenic red pulp, with intense proliferating plasmablasts in the subcapsular and perivascular compartments as well as large numbers of intact P. vivax-infected reticulocytes in the cords, in the absence of other concomitant infectious diseases. To our knowledge, this is the first full detailed immunohistopathological characterization of a nontreated P. vivax-infected spleen.
Note: Reproducció del document publicat a: https://doi.org/10.1371/journal.pntd.0001934
It is part of: PLoS Neglected Tropical Diseases, 2012, vol. 6, num. 12, p. e1934
URI: http://hdl.handle.net/2445/175175
Related resource: https://doi.org/10.1371/journal.pntd.0001934
ISSN: 1935-2735
Appears in Collections:Articles publicats en revistes (Fonaments Clínics)

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