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Title: Update on the Effects of Antioxidants on Diabetic Retinopathy: In Vitro Experiments, Animal Studies and Clinical Trials
Author: Garcia Medina, Jose Javier
Rubio Velazquez, Elena
Foulquie Moreno, Elisa
Casaroli Marano, Ricardo Pedro
Pinazo Duran, Maria Dolores
Zanon Moreno, Vicente
Rio Vellosillo, Monica del
Keywords: Retinopatia diabètica
Estrès oxidatiu
Diabetic retinopathy
Oxidative stress
Issue Date: 1-Jun-2020
Publisher: MDPI
Abstract: Current therapies for diabetic retinopathy (DR) incorporate blood glucose and blood pressure control, vitrectomy, photocoagulation, and intravitreal injections of anti-vascular endothelial growth factors or corticosteroids. Nonetheless, these techniques have not been demonstrated to completely stop the evolution of this disorder. The pathophysiology of DR is not fully known, but there is more and more evidence indicating that oxidative stress is an important mechanism in the progression of DR. In this sense, antioxidants have been suggested as a possible therapy to reduce the complications of DR. In this review we aim to assemble updated information in relation to in vitro experiments, animal studies and clinical trials dealing with the effect of the antioxidants on DR.
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It is part of: Antioxidants, 2020, vol. 9, num. 6
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ISSN: 2076-3921
Appears in Collections:Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

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