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Title: Microblotches on dermoscopy of melanocytic lesions are associated with melanoma: A cross-sectional study
Author: Lukoviek, Vania
Ferrera, Nuria
Podlipnik, Sebastian
Ertekin, Sümeyre S.
Carrera Álvarez, Cristina
Barreiro Capurro, Alicia
Chavez-Bourgeois, Marion
Perino, Francesca
Ortiz-Ruiz, Mauricio
Puigi i Sardà, Susana
Malvehy, J. (Josep)
Keywords: Melanoma
Pronòstic mèdic
Issue Date: 6-Apr-2020
Publisher: Society for the Publication of Acta Dermato-Venereologica
Abstract: Numerous dermoscopic structures for the early detection of melanoma have been described. The aim of this study was to illustrate the characteristics of dermoscopic structures that are similar to blotches, but smaller (termed microblotches), and to evaluate their association with other well-known dermoscopic structures. A cross-sectional study design, including 165 dermoscopic images of melanoma was used to define microblotches, and 241 consecutive images of naevi from the HAM10000 database, were studied to evaluate the prevalence of this criterion in both groups. Microblotches were defined as sharply demarcated structures ≤1 mm, with geographical borders visible only with dermoscopy. Microblotches were present in 38.7% of the melanomas and 6.7% of the naevi. Moreover, microblotches were associated with an odds ratio (OR) of malignancy of 5.79, and were more frequent in invasive melanoma than in the in-situ subtype (OR 2.92). Histologically, they correspond to hyperpigmented parakeratosis or epidermal consumption. In conclusion, microblotches are related to melanomas. This finding could help dermatologists to differentiate between naevi and melanomas.
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It is part of: Acta Dermato-Venereologica, 2020, vol. 100, num. 8
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ISSN: 0001-5555
Appears in Collections:Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

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