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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/176690
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dc.contributor.authorRouaz, Khadija-
dc.contributor.authorChiclana Rodríguez, Blanca-
dc.contributor.authorNardi Ricart, Anna-
dc.contributor.authorSuñé Pou, Marc-
dc.contributor.authorMercadé Frutos, Débora-
dc.contributor.authorSuñé i Negre, Josep M. (Josep Maria)-
dc.contributor.authorPérez Lozano, Pilar-
dc.contributor.authorGarcía Montoya, Encarna-
dc.date.accessioned2021-04-26T09:39:36Z-
dc.date.available2021-04-26T09:39:36Z-
dc.date.issued2021-03-13-
dc.identifier.issn1999-4923-
dc.identifier.urihttp://hdl.handle.net/2445/176690-
dc.description.abstractThis theoretical study seeks to critically review the use of excipients in the paediatric population. This study is based on the rules and recommendations of European and American drug regulatory agencies. On the one hand, this review describes the most frequent excipients used in paediatric medicine formulations, identifying the compounds that scientific literature has marked as potentially harmful regarding the side effects generated after exposure. On the other hand, this review also highlights the importance of carrying out safety -checks on the excipients, which, in most cases, are linked to toxicity studies. An excipient in the compilation of paediatric population databases is expected to target safety and toxicity, as in the STEP database. Finally, a promising pharmaceutical form for child population, ODT (Orally Disintegrating Tablets), will be studied.-
dc.format.extent44 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherMDPI-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/pharmaceutics13030387-
dc.relation.ispartofPharmaceutics, 2021, vol. 13, num. 3, p. 387-
dc.rightscc-by (c) Rouaz, Khadija et al., 2021-
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es-
dc.sourceArticles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)-
dc.subject.classificationExcipients-
dc.subject.classificationPediatria-
dc.subject.classificationToxicologia pediàtrica-
dc.subject.classificationMedicaments-
dc.subject.otherExcipients-
dc.subject.otherPediatrics-
dc.subject.otherPediatric toxicology-
dc.subject.otherDrugs-
dc.titleExcipients in the Paediatric Population: A Review-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec711057-
dc.date.updated2021-04-26T09:39:36Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid33805830-
Appears in Collections:Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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