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http://hdl.handle.net/2445/177205
Title: | The use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department |
Author: | Gutiérrez Miguélez, Cristina Najjari, Dina Martínez, Evelyn Botella, Saray Eraso Urién, Arantxa Pino Sorroche, Francisco Moreno, Ferran Pera Fàbregas, Joan Guedea Edo, Ferran |
Keywords: | Braquiteràpia Càncer de mama Tractament adjuvant del càncer Radioisotope brachytherapy Breast cancer Adjuvant treatment of cancer |
Issue Date: | 1-Jan-2015 |
Publisher: | Polish Brachytherapy Society |
Abstract: | Purpose: to demonstrate the utility of a boost with interstitial brachytherapy (BT) in breast-conserving therapy (BCT) by doing a thorough review of the literature and describing in detail our technique for delivering this boost. Material and methods: our department has been delivering the boost with interstitial BT since 1989, in most cases with rigid needles and a theoretical dosimetry. In the early years, we used low-dose-rate (LDR) with iridium-192 wires. The dose administered was 15 Gy if there were no risk factors for local relapse or 20-25 Gy in the presence of risk factors. The risk factors considered were the presence of a close margin (less than 10 mm) and an extensive intraductal component (more than 25%). After 2002, we switched to high-dose-rate (HDR); using the linear quadratic model we changed the low dose to 3 fractions of 4.5 Gy in the case of no risk factors for local relapse or to 3 fractions of 5 Gy in the presence of risk factors. Results: in 79 consecutive boost patients treated in our department between 2010 and 2011, with a median follow-up of 46 months, the local control rate was 97.47%. With respect to cosmesis, fibrosis occurred in 17 cases (21.5%) and hyperpigmentation in 26 cases (32.9%). Our hospital's results are comparable in terms of local control and cosmesis to those of other authors. Conclusions: this educational article describes our department's boost technique with rigid needles and comments briefly on our results using this technique in a group of consecutively treated patients in our department. A review of the literature and the published results on local control and cosmesis is also described. |
Note: | Reproducció del document publicat a: https://doi.org/10.5114/jcb.2014.46757 |
It is part of: | Journal of Contemporary Brachytherapy, 2015, vol. 6, num. 4, p. 397-403 |
URI: | http://hdl.handle.net/2445/177205 |
Related resource: | https://doi.org/10.5114/jcb.2014.46757 |
ISSN: | 1689-832X |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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660874.pdf | 331.26 kB | Adobe PDF | View/Open |
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