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http://hdl.handle.net/2445/177455
Title: | Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics |
Author: | Gironés Petit, Robert Cano Fernández, Amanda Ortiz Rodrigo, Alba Espina García, Marta Prat Aixelà, Josefa Muñoz Juncosa, Montserrat Severino, Patrícia Souto, Eliana B. García López, María Luisa Pujol Cubells, Montserrat Sánchez-López, E. (Elena) |
Keywords: | Malalties de la pell Psoriasi Dermatitis Skin diseases Psoriasis Dermatitis |
Issue Date: | 7-May-2021 |
Publisher: | MDPI |
Abstract: | Research in the pathogenesis of inflammatory skin diseases, such as skin dermatitis and psoriasis, has experienced some relevant breakthroughs in recent years. The understanding of age-related factors, gender, and genetic predisposition of these multifactorial diseases has been instrumental for the development of new pharmacological and technological treatment approaches. In this review, we discuss the molecular mechanisms behind the pathological features of psoriasis, also addressing the currently available treatments and novel therapies that are under clinical trials. Innovative therapies developed over the last 10 years have been researched. In this area, advantages of nanotechnological approaches to provide an effective drug concentration in the disease site are highlighted, together with microneedles as innovative candidates for drug delivery systems in psoriasis and other inflammatory chronic skin diseases. View Full-Text Keywords: skin inflammatory diseases; psoriasis; psoriasis versus atopic dermatitis; biodegradable nanoparticles; microneedles; clinical trials |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/ijms22094983 |
It is part of: | International Journal of Molecular Sciences, 2021, vol. 22, num. 9, p. 4983 |
URI: | http://hdl.handle.net/2445/177455 |
Related resource: | https://doi.org/10.3390/ijms22094983 |
ISSN: | 1661-6596 |
Appears in Collections: | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) |
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