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http://hdl.handle.net/2445/177690
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DC Field | Value | Language |
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dc.contributor.author | Cubero, Meritxell | - |
dc.contributor.author | Grau, Immaculada | - |
dc.contributor.author | Tubau, Fe | - |
dc.contributor.author | Pallarés Giner, Roman | - |
dc.contributor.author | Domínguez Luzón, Ma. Ángeles (María Ángeles) | - |
dc.contributor.author | Liñares Louzao, Josefina | - |
dc.contributor.author | Ardanuy Tisaire, María Carmen | - |
dc.date.accessioned | 2021-05-27T14:34:46Z | - |
dc.date.available | 2021-05-27T14:34:46Z | - |
dc.date.issued | 2018-09-01 | - |
dc.identifier.issn | 1076-6294 | - |
dc.identifier.uri | http://hdl.handle.net/2445/177690 | - |
dc.description.abstract | Molecular epidemiology of Klebsiella pneumoniae bacteremic strains allows for a better understanding of preventive and therapeutic strategies. Clinical and microbiological characteristics of 348 K. pneumoniae bacteremia cases (2007-2009) were retrospectively characterized by multilocus sequence typing and extended-spectrum beta-lactamases (ESBL) production. Overall, 223 (64.08%) cases were nosocomial (NA), 58 (16.67%) healthcare associated, and 67 (19.25%) community acquired. The main infection origins were urinary tract (16.6%, 50.0%, and 43.3%), biliary tract (10.8%, 24.2%, and 31.3%), and catheter-related infection (39.9%, 5.2%, and 0%). The 30-day mortality rate was around 20%. The rates of resistance were around 45% the highest being among NA cases, and ESBL production was detected in 7.2% of cases. A total of 161 different sequence types were grouped into 13 clonal sets by e-burst analysis. No relationship could be established between clonal sets and the origin of infection or the healthcare-related settings. The high genetic variability among the isolates suggests their intrapatient endogenous origin. | - |
dc.format.extent | 9 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Mary Ann Liebert | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1089/mdr.2017.0107 | - |
dc.relation.ispartof | Microbial Drug Resistance, 2018, vol. 24, num. 7, p. 949-957 | - |
dc.relation.uri | https://doi.org/10.1089/mdr.2017.0107 | - |
dc.rights | (c) Mary Ann Liebert, 2018 | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Microbiologia | - |
dc.subject.classification | Klebsiella pneumoniae | - |
dc.subject.classification | Genètica | - |
dc.subject.other | Microbiology | - |
dc.subject.other | Klebsiella pneumoniae | - |
dc.subject.other | Genetics | - |
dc.title | Molecular Epidemiology of Klebsiella pneumoniae Strains Causing Bloodstream Infections in Adults | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 677829 | - |
dc.date.updated | 2021-05-27T14:34:46Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 29227744 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Patologia i Terapèutica Experimental) |
Files in This Item:
File | Description | Size | Format | |
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677829.pdf | 411.09 kB | Adobe PDF | View/Open |
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