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Title: Determinants and impact of suboptimal anthma control in Europe: the international cross-sectional and longitudinal assessment on asthma control (Liaison study)
Author: Braido, Fulvio
Brusselle, Guy
Guastalla, Daniele
Ingrassia, Eleonora
Nicolini, Gabriele
Price, David
Roche, Nicolas
Soriano, Joan B.
Worth, Heinrich
Lores Obradors, Luis
Liasion Study Group
Keywords: Asma
Qualitat de vida
Quality of life
Issue Date: 14-May-2016
Publisher: BioMed Central
Abstract: Background: according to the Global Initiative of Asthma, the aim of asthma treatment is to gain and maintain control. In the INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study, we evaluated the level of asthma control and quality of life (QoL), as well as their determinants and impact in a population consulting specialist settings. Methods: LIAISON is a prospective, multicentre, observational study with a cross-sectional and a 12-month longitudinal phase. Adults with an asthma diagnosis since at least 6 months, receiving the same asthma treatment in the 4 weeks before enrolment were included. Asthma control was assessed with the 6-item Asthma Control Questionnaire (ACQ) and QoL with the MiniAsthma Quality of Life Questionnaire (MiniAQLQ). Results: overall, 8111 asthmatic patients were enrolled in 12 European countries. Asthma control was suboptimal in 56.5 % of patients and it was associated with poorer asthma-related QoL, higher risk of exacerbations and greater consumption of healthcare resources. Variables associated with suboptimal control were age, gender, obesity, smoking and comorbidities. Major determinants of poor asthma control were seasonal worsening and persisting exposure to allergens/irritants/triggers, followed by treatment-related issues. Conclusions: the cross-sectional phase results confirm that suboptimal control is frequent and has a high individual and economic impact. Trial registration: The identifier is NCT01567280 .
Note: Reproducció del document publicat a:
It is part of: Respiratory Research, 2016, vol. 17, num. 1, p. 51
Related resource:
ISSN: 1465-993X
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)

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