Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/178363
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Baena Díez, José Miguel | - |
dc.contributor.author | Peñafiel, Judith | - |
dc.contributor.author | Subirana, Isaac | - |
dc.contributor.author | Ramos, Rafel | - |
dc.contributor.author | Elosua, Roberto | - |
dc.contributor.author | Marín Ibánez, Alejandro | - |
dc.contributor.author | Jesús Guembe, María | - |
dc.contributor.author | Rigo, Fernando | - |
dc.contributor.author | José Tormo Díaz, Maria | - |
dc.contributor.author | Moreno Iribas, Conchi | - |
dc.contributor.author | Josep Cabré, Joan | - |
dc.contributor.author | Segura, Antonio | - |
dc.contributor.author | García Lareo, Manel | - |
dc.contributor.author | Gomez de la Carnara, Agustin | - |
dc.contributor.author | Lapetra, José | - |
dc.contributor.author | Quesada, Miquel | - |
dc.contributor.author | Marrugat, Jaume, 1954- | - |
dc.contributor.author | Jose Medrano, Maria | - |
dc.contributor.author | Berjón, Jesus | - |
dc.contributor.author | Frontera, Guillem | - |
dc.contributor.author | Gavrila, Diana | - |
dc.contributor.author | Barricarte, Aurelio | - |
dc.contributor.author | Basora, Josep | - |
dc.contributor.author | María García, Jose | - |
dc.contributor.author | Pavone, Natalia C. | - |
dc.contributor.author | Lora Pablos, David | - |
dc.contributor.author | Mayoral, Eduardo | - |
dc.contributor.author | Franch Nadal, Josep | - |
dc.contributor.author | Mata Cases, Manel | - |
dc.contributor.author | Castell, Conxa | - |
dc.contributor.author | Frances, Albert | - |
dc.contributor.author | Grau, Maria | - |
dc.date.accessioned | 2021-06-14T15:18:53Z | - |
dc.date.available | 2021-06-14T15:18:53Z | - |
dc.date.issued | 2016-11-01 | - |
dc.identifier.issn | 0149-5992 | - |
dc.identifier.uri | http://hdl.handle.net/2445/178363 | - |
dc.description.abstract | OBJECTIVE: Diabetes is a common cause of shortened life expectancy. We aimed to assess the association between diabetes and cause-specific death. RESEARCH DESIGN AND METHODS: We used the pooled analysis of individual data from 12 Spanish population cohorts with 10-year follow-up. Participants had no previous history of cardiovascular diseases and were 35-79 years old. Diabetes status was self-reported or defined as glycemia >125 mg/dL at baseline. Vital status and causes of death were ascertained by medical records review and linkage with the official death registry. The hazard ratios and cumulative mortality function were assessed with two approaches, with and without competing risks: proportional subdistribution hazard (PSH) and cause-specific hazard (CSH), respectively. Multivariate analyses were fitted for cardiovascular, cancer, and noncardiovascular noncancer deaths.RESULTSWe included 55,292 individuals (15.6% with diabetes and overall mortality of 9.1%). The adjusted hazard ratios showed that diabetes increased mortality risk: 1) cardiovascular death, CSH = 2.03 (95% CI 1.63-2.52) and PSH = 1.99 (1.60-2.49) in men; and CSH = 2.28 (1.75-2.97) and PSH = 2.23 (1.70-2.91) in women; 2) cancer death, CSH = 1.37 (1.13-1.67) and PSH = 1.35 (1.10-1.65) in men; and CSH = 1.68 (1.29-2.20) and PSH = 1.66 (1.25-2.19) in women; and 3) noncardiovascular non cancer death, CSH = 1.53 (1.23-1.91) and PSH = 1.50 (1.20-1.89) in men; and CSH = 1.89 (1.43-2.48) and PSH = 1.84 (1.39-2.45) in women. In all instances, the cumulative mortality function was significantly higher in individuals with diabetes. CONCLUSIONS: Diabetes is associated with premature death from cardiovascular disease, cancer, and noncardiovascular noncancer causes. The use of CSH and PSH provides a comprehensive view of mortality dynamics in a population with diabetes. | - |
dc.format.extent | 29 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | American Diabetes Association | - |
dc.relation.isformatof | https://doi.org/10.2337/dc16-0614 | - |
dc.relation.ispartof | Diabetes Care, 2016, vol. 39, num. 11, p. 1987-1995 | - |
dc.relation.uri | https://doi.org/10.2337/dc16-0614 | - |
dc.rights | , 2016 | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Diabetis | - |
dc.subject.other | Diabetes | - |
dc.title | Risk of Cause-Specific Death in Individuals With Diabetes: A Competing Risks Analysis | - |
dc.type | info:eu-repo/semantics/article | - |
dc.identifier.idgrec | 679772 | - |
dc.date.updated | 2021-06-14T15:18:53Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27493134 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
679772.pdf | 731.98 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.