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Title: Calculation of portal contribution to hepatic blood flow with 99mTc-microcolloids. A noninvasive method to diagnose liver graft rejection
Author: Martín-Comín, Josep
Mora Salvador, Jaume
Figueras Felip, Joan
Puchal Añé, Rafael
Jaurrieta Mas, Eduardo
Badosa i Coll, Ferran
Ramos Márquez, Miguel
Keywords: Rebuig (Biologia)
Diagnòstic per la imatge
Graft rejection
Diagnostic imaging
Issue Date: 1-Nov-1988
Publisher: The Society of Nuclear Medicine and Molecular Imaging
Abstract: The portal contribution (PC) to hepatic blood flow was calculated in 13 liver graft patients and 13 normal volunteers. The method is based on the quantification and normalization of the liver and spleen activity after the administration of 7 mCi (259 MBq) of 99mTc microcolloid. Forty examinations were performed in liver grafts and 13 in normal subjects. The PC was significantly higher in normal native liver (64.0 +/- 3.0%) than in functioning grafts (58.8 +/- 3.1%). In acutely rejecting patients, PC was significantly lower (52.4 +/- 2.0%) than in functioning grafts and similar to that observed in cholangitis (53.5 +/- 0.7%). The PC increases again once rejection has resolved (57.3 +/- 2.6%). During hepatitis post-transplant PC values (59.7 +/- 3.4%) were similar to those observed in functioning grafts. Overall, PC values over 55% are very unlikely to be due to rejection.
Note: Reproducció del document publicat a:
It is part of: Journal of Nuclear Medicine, 1988, vol. 29, num. 11, p. 1776-1780
ISSN: 0161-5505
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)

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