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Title: ENIGMA-anxiety working group: Rationale for and organization of large-scale neuroimaging studies of anxiety disorders
Author: Bas Hoogendam, Janna Marie
Groenewold, Ninke A.
Aghajani, Moji
Freitag, Gabrielle F.
Harrewijn, Anita
Hilbert, Kevin
Jahanshad, Neda
Thomopoulos, Sophia I.
Thompson, Paul M.
Veltman, Dick J.
Winkler, Anderson M.
Lueken, Ulrike
Pine, Daniel S.
van der Wee, Nick J. A.
Stein, Dan J.
ENIGMA-Anxiety Working Group
Fañanás Saura, Lourdes
Keywords: Ansietat
Imatges per ressonància magnètica
Magnetic resonance imaging
Issue Date: 3-Jul-2020
Publisher: Wiley
Abstract: Anxiety disorders are highly prevalent and disabling but seem particularly tractable to investigation with translational neuroscience methodologies. Neuroimaging has informed our understanding of the neurobiology of anxiety disorders, but research has been limited by small sample sizes and low statistical power, as well as heterogenous imaging methodology. The ENIGMA‐Anxiety Working Group has brought together researchers from around the world, in a harmonized and coordinated effort to address these challenges and generate more robust and reproducible findings. This paper elaborates on the concepts and methods informing the work of the working group to date, and describes the initial approach of the four subgroups studying generalized anxiety disorder, panic disorder, social anxiety disorder, and specific phobia. At present, the ENIGMA‐Anxiety database contains information about more than 100 unique samples, from 16 countries and 59 institutes. Future directions include examining additional imaging modalities, integrating imaging and genetic data, and collaborating with other ENIGMA working groups. The ENIGMA consortium creates synergy at the intersection of global mental health and clinical neuroscience, and the ENIGMA‐Anxiety Working Group extends the promise of this approach to neuroimaging research on anxiety disorders.
Note: Reproducció del document publicat a:
It is part of: Human Brain Mapping, 2020, num. 2020
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ISSN: 1065-9471
Appears in Collections:Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)

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