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DC Field | Value | Language |
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dc.contributor.author | Koban, Leonie | - |
dc.contributor.author | Jepma, Marieke | - |
dc.contributor.author | López-Solà, Marina | - |
dc.contributor.author | Wager Tor D. | - |
dc.date.accessioned | 2021-07-20T12:36:09Z | - |
dc.date.available | 2021-07-20T12:36:09Z | - |
dc.date.issued | 2019-09-10 | - |
dc.identifier.issn | 2041-1723 | - |
dc.identifier.uri | http://hdl.handle.net/2445/179239 | - |
dc.description.abstract | Information about others' experiences can strongly influence our own feelings and decisions. But how does such social information affect the neural generation of affective experience, and are the brain mechanisms involved distinct from those that mediate other types of expectation effects? Here, we used fMRI to dissociate the brain mediators of social influence and associative learning effects on pain. Participants viewed symbolic depictions of other participants' pain ratings (social information) and classically conditioned pain-predictive cues before experiencing painful heat. Social information and conditioned stimuli each had significant effects on pain ratings, and both effects were mediated by self-reported expectations. Yet, these effects were mediated by largely separable brain activity patterns, involving different large-scale functional networks. These results show that learned versus socially instructed expectations modulate pain via partially different mechanisms-a distinction that should be accounted for by theories of predictive coding and related top-down influences. | - |
dc.format.extent | 13 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1038/s41467-019-11934-y | - |
dc.relation.ispartof | Nature Communications, 2019, vol. 10, num. 1, p. 4096-4096 | - |
dc.relation.uri | https://doi.org/10.1038/s41467-019-11934-y | - |
dc.rights | cc-by (c) Koban, Leonie et al., 2019 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Fisiologia patològica | - |
dc.subject.classification | Dolor | - |
dc.subject.classification | Ressonància magnètica | - |
dc.subject.other | Pathological physiology | - |
dc.subject.other | Pain | - |
dc.subject.other | Magnetic resonance | - |
dc.title | Different brain networks mediate the effects of social and conditioned expectations on pain. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 698757 | - |
dc.date.updated | 2021-07-20T12:36:09Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 31506426 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
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698757.pdf | 3.47 MB | Adobe PDF | View/Open |
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