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http://hdl.handle.net/2445/179784| Title: | Modified siRNAs for the study of the PAZ domain |
| Author: | Somoza, Álvaro Terrazas Martínez, Montserrat Eritja i Casadellà, Ramon |
| Keywords: | RNA Fixació de proteïnes Modificació química de les proteïnes RNA Protein binding Chemical modification of proteins |
| Issue Date: | 19-May-2010 |
| Publisher: | Royal Society of Chemistry |
| Abstract: | Chemical modifications aimed at stabilizing the interaction between the 3'-end of siRNAs and the PAZ domain of RISC have been tested for their effect on RNAi activity. Such modifications contribute positively to the stability of siRNAs in human serum. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1039/C003221B |
| It is part of: | Chemical Communications, 2010, vol. 46, p. 4270-4272 |
| URI: | http://hdl.handle.net/2445/179784 |
| Related resource: | https://doi.org/10.1039/C003221B |
| ISSN: | 1359-7345 |
| Appears in Collections: | Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona)) Articles publicats en revistes (Química Inorgànica i Orgànica) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 713433.pdf | 1.13 MB | Adobe PDF | View/Open |
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